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Do SGLT2 inhibitors improve cardiac & vascular function versus placebo?

Also asked against other treatments.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

A coin flip. So far, the results disagree.

NoUnsureYes
Belief
0.50 (range 0.00–0.55)
Trials for
6
Trials against
3
Inconclusive
2

Already under way

No registered trial that could settle this is recruiting or active.

The evidence so far

Registered trials
229
With posted results
31
Published papers
3

Of 26 decided analyses: 8 favor sglt2 inhibitors, 18 find no difference, 0 favor the comparator.

Papers

Trials

See every trial in the evidence map →