Closing

Does metformin improve blood pressure versus placebo?

Mostly studied in type 2 & unspecified diabetes. Also asked against other treatments.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

A coin flip. So far, the results disagree.

NoUnsureYes
Belief
0.40 (range 0.00–0.55)
Trials for
1
Trials against
1
Inconclusive
2

Already under way

The evidence so far

Registered trials
184
With posted results
65
Published papers
13

Of 9 decided analyses: 2 favor metformin, 5 find no difference, 2 favor the comparator.

Papers

Trials

See every trial in the evidence map →