Closing

Does metformin improve blood pressure more than other treatments?

Mostly studied in type 2 & unspecified diabetes. Also asked versus placebo.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

A coin flip. So far, one result, not yet repeated.

NoUnsureYes
Belief
0.50 (range 0.25–0.70)
Trials for
1
Trials against
0
Inconclusive
1

Already under way

The evidence so far

Registered trials
184
With posted results
65
Published papers
13

Of 9 decided analyses: 2 favor metformin, 5 find no difference, 2 favor the comparator.

Papers

Trials

See every trial in the evidence map →