Settled

Do SGLT2 inhibitors improve blood pressure versus placebo?

Mostly studied in type 2 & unspecified diabetes. Also asked against other treatments.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

Very likely. So far, established.

NoUnsureYes
Belief
0.88 (range 0.65–0.97)
Trials for
14
Trials against
2
Inconclusive
16

Already under way

The evidence so far

Registered trials
252
With posted results
78
Published papers
8

Of 144 decided analyses: 78 favor sglt2 inhibitors, 64 find no difference, 2 favor the comparator.

Papers

Trials

See every trial in the evidence map →