Closing

Do PCSK9 inhibitors improve costs & health-care use versus placebo?

Mostly studied in coronary & atherosclerotic disease.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

A coin flip. So far, one result, not yet repeated.

NoUnsureYes
Belief
0.50 (range 0.25–0.70)
Trials for
1
Trials against
0
Inconclusive
0

Already under way

The evidence so far

Registered trials
6
With posted results
1
Published papers
0

Of 2 decided analyses: 2 favor pcsk9 inhibitors, 0 find no difference, 0 favor the comparator.

Trials

See every trial in the evidence map →