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Does other glucose-lowering improve cardiovascular events more than other treatments?
Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →
Where the evidence stands
No claim has formed for this comparison yet. The trials below are registered, but none decides it.
Already under way
No registered trial that could settle this is recruiting or active.
The evidence so far
- Registered trials
- 3
- With posted results
- 1
- Published papers
- 6
Papers
- Metformin and second- or third-generation sulphonylurea combination therapy for adults with type 2 diabetes mellitus.Meta-analysis / systematic review · 2019
- Alpha-glucosidase inhibitors for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased risk of developing type 2 diabetes mellitus.Meta-analysis / systematic review · 2018
- Cardiovascular outcomes associated with SGLT-2 inhibitors versus other glucose-lowering drugs in patients with type 2 diabetes: A real-world systematic review and meta-analysis.Meta-analysis / systematic review · 2021
- Novel antidiabetic drugs and risk of cardiovascular events in patients without baseline metformin use: a meta-analysis.Meta-analysis / systematic review · 2021
- Cardiovascular risks associated with second-line oral antidiabetic agents added to metformin in patients with Type 2 diabetes: a nationwide cohort study.Observational study · 2015
- Cardiovascular mortality and morbidity in patients with type 2 diabetes following initiation of sodium-glucose co-transporter-2 inhibitors versus other glucose-lowering drugs (CVD-REAL Nordic): a multinational observational analysis.Observational study · 2017
Trials
- Dapagliflozin Effect in Cognitive Impairment in Stroke TrialNCT05565976
- Carotid Plaque Composition by Magnetic Resonance Imaging During Lipid Lowering TherapyNCT00715273 · 1 posted result
- Incretin-based Drugs and the Risk of Heart Failure: A Multi-center Network Observational StudyNCT02456428