Closing

Does metformin improve body weight & composition more than other treatments?

Mostly studied in gestational diabetes & pregnancy. Also asked versus placebo.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

Unlikely. So far, the results disagree.

NoUnsureYes
Belief
0.00 (range 0.00–0.55)
Trials for
0
Trials against
3
Inconclusive
5

Already under way

The evidence so far

Registered trials
457
With posted results
154
Published papers
30

Of 38 decided analyses: 14 favor metformin, 17 find no difference, 7 favor the comparator.

Papers

Trials

See every trial in the evidence map →