Closing

Does metformin improve pharmacokinetics & dosing more than other treatments?

Mostly studied in type 2 & unspecified diabetes. Also asked versus placebo.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

Doubtful. So far, no trial evidence yet.

NoUnsureYes
Belief
0.25 (range 0.10–0.70)
Trials for
0
Trials against
0
Inconclusive
1

Already under way

The evidence so far

Registered trials
192
With posted results
60
Published papers
11

Of 3 decided analyses: 0 favor metformin, 3 find no difference, 0 favor the comparator.

Papers

Trials

See every trial in the evidence map →