Closing

Do GLP-1 receptor agonists improve cardiovascular events versus placebo?

Mostly studied in heart failure. Also asked against other treatments.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

A coin flip. So far, the results disagree.

NoUnsureYes
Belief
0.50 (range 0.00–0.55)
Trials for
7
Trials against
3
Inconclusive
1

Already under way

The evidence so far

Registered trials
102
With posted results
44
Published papers
33

Of 61 decided analyses: 19 favor glp-1 receptor agonists, 34 find no difference, 8 favor the comparator.

Papers

Trials

See every trial in the evidence map →