Settled

Do GIP/GLP-1 & amylin agonists improve body weight & composition versus placebo?

Mostly studied in heart failure. Also asked against other treatments.

Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →

Where the evidence stands

Very likely. So far, repeated by independent trials.

NoUnsureYes
Belief
1.00 (range 0.85–1.00)
Trials for
19
Trials against
0
Inconclusive
2

Already under way

The evidence so far

Registered trials
165
With posted results
31
Published papers
25

Of 231 decided analyses: 213 favor gip/glp-1 & amylin agonists, 14 find no difference, 4 favor the comparator.

Papers

Trials

See every trial in the evidence map →