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Do antiplatelet & anticoagulant cause more adverse events & safety versus placebo?
Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →
Where the evidence stands
Doubtful. So far, no trial evidence yet.
NoUnsureYes
- Belief
- 0.25 (range 0.10–0.70)
- Trials for
- 0
- Trials against
- 0
- Inconclusive
- 1
Already under way
No registered trial that could settle this is recruiting or active.
The evidence so far
- Registered trials
- 33
- With posted results
- 4
- Published papers
- 5
Of 2 decided analyses: 0 favor antiplatelet & anticoagulant, 1 find no difference, 1 favor the comparator.
Papers
- Association of metformin, aspirin, and cancer incidence with mortality risk in adults with diabetes.Trial report · 2023
- Pharmacological interventions for asymptomatic carotid stenosis.Meta-analysis / systematic review · 2023
- Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups.Meta-analysis / systematic review · 2019
- Determining optimal strategies for primary prevention of cardiovascular disease: a synopsis of an evidence synthesis study.Meta-analysis / systematic review · 2025
- Drugs for Primary Prevention of Atherosclerotic Cardiovascular Disease: An Overview of Systematic Reviews.Meta-analysis / systematic review · 2016
Trials
- Role of Innate and Adaptive Immunity After Acute Myocardial Infarction BATTLE-AMI Study (B And T Types of Lymphocytes Evaluation in Acute Myocardial Infarction)NCT02428374
- Improving Equitable Acces and Adherence to Secondary Prevention Therapy With a Fixed-Dose Combination DrugNCT01321255
- PROgnostic Value of Precision Medicine in Patients With Myocardial Infarction and Non-obStructive Coronary artEries: the PROMISE Trial.NCT05122780
- A Multicenter, Randomized, Controlled, Double-Blind Trial to Investigate the Clinical Efficacy and Tolerability of Early Treatment With Simvastatin 40 mg Daily for 30 Days, Followed by Simvastatin 80 mg Daily Thereafter in Tirofiban-Treated Acute Coronary Syndrome Patients Who Have Been Randomized to Receive Enoxaparin or Unfractionated Heparin in Conjunction With AspirinNCT00251576
- Efficacy and Safety of Chinese Herbal Medicine Wen Xin Granules for the Treatment of Unstable Angina Pectoris With Yang Deficiency and Blood Stasis Syndrome: Study Protocol for a Randomized Controlled TrialNCT04661709
- Evaluation of a POlypill and Colchicine for Risk Reduction in Patients With Established Atherosclerotic Cardiovascular Disease: The EPOCA Randomized Clinical TrialNCT06930885
- The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy)NCT02767401
- Development of a Risk Prediction Algorithm Through the Investigation of Genetic Risk Factors and the Complexity of Coronary Artery Disease to Estimate Future Risk of Cardiovascular Events: Angiographic (SYNTAX Score), Clinical and Pharmacogenetic Analysis.NCT03150680