Open
Do anti-obesity drugs improve adverse events & safety more than other treatments?
Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →
Where the evidence stands
No claim has formed for this comparison yet. The trials below are registered, but none decides it.
Already under way
No registered trial that could settle this is recruiting or active.
The evidence so far
- Registered trials
- 8
- With posted results
- 3
- Published papers
- 2
Papers
- Long-term effects of weight-reducing drugs in people with hypertension.Meta-analysis / systematic review · 2026
- Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis.Meta-analysis / systematic review · 2016
Trials
- Double-blind, Randomized Clinical Trial to Evaluate Effect of Combination Therapy of Metformin and Sibutramine Versus Metformin or Sibutramine Monotherapy Over Weight, Adiposity, Glucose Metabolism and Inflammatory State in Obese PatientsNCT00941382
- Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes vs Best Medical TreatmentNCT02041234
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Investigate the Safety and Efficacy of the Co-administration of Canagliflozin 300 mg and Phentermine 15 mg Compared With Placebo for the Treatment of Non-diabetic Overweight and Obese SubjectsNCT02243202 · 1 posted result
- Analysis of Changes in Intestinal Flora of Hyperlipidemia by Ezetimibe and Orlistat.NCT03884127
- Combining Lifestyle Modification and Liraglutide to Improve Weight Loss and Health OutcomesNCT02911818 · 2 posted results
- Does Reversal of Visceral Obesity by Drug Therapy Improve Vascular Function?NCT01351753 · 1 posted result
- Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder - OBOE-MayoNCT07213466
- The Therapeutic Effects of Topiramate and Metformin on Second Generation Antipsychotics-induced ObesityNCT01384279