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Do anti-obesity drugs improve blood pressure versus placebo?
Mostly studied in obesity & overweight.
Not modeled yetTrial evidence exists, but no mechanistic model yetWithout a model there is no decisive experiment to propose. Help build it. →
Where the evidence stands
Doubtful. So far, no trial evidence yet.
NoUnsureYes
- Belief
- 0.25 (range 0.10–0.70)
- Trials for
- 0
- Trials against
- 0
- Inconclusive
- 1
Already under way
No registered trial that could settle this is recruiting or active.
The evidence so far
- Registered trials
- 9
- With posted results
- 6
- Published papers
- 0
Of 1 decided analyses: 0 favor anti-obesity drugs, 1 find no difference, 0 favor the comparator.
Trials
- A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Investigate the Safety and Efficacy of the Co-administration of Canagliflozin 300 mg and Phentermine 15 mg Compared With Placebo for the Treatment of Non-diabetic Overweight and Obese SubjectsNCT02243202 · 4 posted results
- Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes vs Best Medical TreatmentNCT02041234
- Effect of Liraglutide on Body Weight in Obese Subjects Without Diabetes: A 20-week Randomised, Double-blind, Placebo-controlled, Six Armed Parallel Group, Multi-centre, Multinational Trial With an Open Label Orlistat Comparator Arm and With an 84-week Extension PeriodNCT00422058 · 2 posted results
- Phase 1-2 Study of Development of Rational Ways of Medical and Non-medical Treatment Methods for Metabolic SyndromeNCT02503865 · 1 posted result
- A Prospective Randomized Study Evaluating the Efficacy of Pharmacotherapy to Enhance Weight Loss Following Sleeve GastrectomyNCT03603080
- Cardiovascular and Metabolic Effects of Drugs for the Treatment of ObesityNCT04575194
- Combining Lifestyle Modification and Liraglutide to Improve Weight Loss and Health OutcomesNCT02911818 · 4 posted results
- Comparison of Dapagliflozin (DAPA) and Once-weekly Exenatide (EQW), Co-administered or Alone, DAPA/ Glucophage (DAPA/MET ER) and Phentermine/Topiramate (PHEN/TPM) ER on Metabolic Profiles and Body Composition in Obese PCOS WomenNCT02635386 · 2 posted results