Evidence map›Paper›PMID 29542032›Full record

ArticleProbiotics and antimicrobial proteins2019

Lactobacillus casei and Lactobacillus fermentum Strains Isolated from Mozzarella Cheese: Probiotic Potential, Safety, Acidifying Kinetic Parameters and Viability under Gastrointestinal Tract Conditions.

Bruna Maria Salotti de Souza, Taís Fernanda Borgonovi, Sabrina Neves Casarotti, Svetoslav Dimitrov Todorov, Ana Lúcia Barretto Penna

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 164 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Antibiotic susceptibility of lactic acid bacteria isolated from artisanal coalho cheese in the Agreste region of Pernambuco, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  8. Article
  9. Article
  10. Probiotic properties ofFrontiers in microbiology · 2026
    Article
  11. Article
  12. Synergistic probiotic consortium ofVeterinary world · 2025
    Article
  13. Lactococcus lactis GV103, potentially probiotic, applied in the development of lactose-free fermented milk.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Fruit-Based Diet and Gut Health: A Review.Food science & nutrition · 2025
    Review
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Bruna Maria Salotti de SouzaDepartment Food Engineering and Technology, Sao Paulo State University, Rua Cristóvão Colombo, 2265, Jardim Nazareth, São José Preto, SP, 15.0540-000, Brazil.
Taís Fernanda BorgonoviDepartment Food Engineering and Technology, Sao Paulo State University, Rua Cristóvão Colombo, 2265, Jardim Nazareth, São José Preto, SP, 15.0540-000, Brazil.
Sabrina Neves CasarottiFaculty of Nutrition, Department of Food and Nutrition, UFMT - Mato Grosso Federal University, Cuiabá, MT, Brazil.
Svetoslav Dimitrov TodorovFaculty of Pharmaceutical Sciences, Department of Food Science and Experimental Nutrition, USP - São Paulo University, São Paulo, SP, Brazil.
Ana Lúcia Barretto PennaDepartment Food Engineering and Technology, Sao Paulo State University, Rua Cristóvão Colombo, 2265, Jardim Nazareth, São José Preto, SP, 15.0540-000, Brazil. analucia@ibilce.unesp.br.
Universidade Estadual Paulista (Unesp) · BRUniversidade de São Paulo · BRUniversidade Federal de Mato Grosso · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to evaluate the probiotic properties of Lactobacillus casei and Lactobacillus fermentum strains, as well as to select novel and safe strains for future development of functional fermented products. The in vitro auto-aggregation, co-aggregation, hydrophobicity, β-galactosidase production, survival to gastrointestinal tract (GIT), and antibiotic susceptibility were evaluated. The selected strains were additionally tested by the presence of genes encoding adhesion, aggregation and colonization, virulence factors, antibiotic resistance, and biogenic amine production, followed by the evaluation of acidifying kinetic parameters in milk, and survival of the strains under simulated GIT conditions during refrigerated storage of fermented milk. Most strains of both species showed high auto-aggregation; some strains showed co-aggregation ability with other lactic acid bacteria (LAB) and/or pathogens, and both species showed low hydrophobicity values. Seven L. casei and six L. fermentum strains produced β-galactosidase enzymes, and ten strains survived well the simulation of the GIT stressful conditions evaluated in vitro. All strains were resistant to vancomycin, and almost all the strains were resistant to kanamycin. L. casei SJRP38 and L. fermentum SJRP43 were distinguished among the other LAB strains by their higher probiotic potential. L. fermentum SJRP43 presented fewer genes related to virulence factors and antibiotic resistance and needed more time to reach the maximum acidification rate (V

Indexed as

Microbial ViabilityAnimalsAnti-Bacterial Agentsbeta-GalactosidaseCheeseFermentationGastrointestinal TractHydrophobic and Hydrophilic InteractionsKineticsLacticaseibacillus caseiLimosilactobacillus fermentumMilkProbioticsAnti-Bacterial Agentsbeta-GalactosidaseBeneficial effectsIntestinal microorganismsLactic acid bacteriaProbiotic microorganisms

Identifiers

PMID29542032
OpenAlexW2793168114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.