← SGLT2 inhibitors × cardiovascular events

Observational studyDiabetes, obesity & metabolism2018

Risk of lower extremity amputations in people with type 2 diabetes mellitus treated with sodium-glucose co-transporter-2 inhibitors in the USA: A retrospective cohort study.

Zhong Yuan et al.PubMed ↗Full text ↗Publisher ↗

What moved togetherboth groups pooled, not the treatment’s effect

Correlation · may be no link

No clear link with cardiovascular events

−2%−32% to +41%

Smaller than almost all for cardiovascular events

As reported

HR 0.98, 95% CI 0.68–1.41

One number in the abstract

the abstract, start to end

… AHAs, respectively; the hazard ratio was 0.98 (95% confidence interval …

← favours treatmentfavours comparator →
could be chance
Cardiovascular events
HR 0.980.68–1.41
SGLT2 inhibitorsCardiovascular events
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