ArticleGenetics1996
The efficiency of meiotic recombination between dispersed sequences in Saccharomyces cerevisiae depends upon their chromosomal location.
Article in Genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed.
- Chromosome movements in meiotic prophase: regulatory mechanisms and biological roles.Frontiers in cell and developmental biology · 2026Review
- Holocentric repeat landscapes: From micro-evolutionary patterns to macro-evolutionary associations with karyotype evolution.Molecular ecology · 2024Article
- Article
- Meiosis in budding yeast.Genetics · 2023Article
- The Role of Repetitive Sequences in Repatterning of Major Ribosomal DNA Clusters in Lepidoptera.Genome biology and evolution · 2023Article
- Karyotype differentiation and male meiosis in European clades of the spider genusComparative cytogenetics · 2022Article
- Article
- A mutant form of Dmc1 that bypasses the requirement for accessory protein Mei5-Sae3 reveals independent activities of Mei5-Sae3 and Rad51 in Dmc1 filament stability.PLoS genetics · 2019Article
- Modeling meiotic chromosome pairing: a tug of war between telomere forces and a pairing-based Brownian ratchet leads to increased pairing fidelity.Physical biology · 2019Article
- Molecular technique reveals high variability of 18S rDNA distribution in harvestmen (Opiliones, Phalangiidae) from South Africa.Comparative cytogenetics · 2018Article
- The relationship of recombination rate, genome structure, and patterns of molecular evolution across angiosperms.BMC evolutionary biology · 2015Article
- Cell biology of mitotic recombination.Cold Spring Harbor perspectives in biology · 2015Review
- Mechanisms and principles of homology search during recombination.Nature reviews. Molecular cell biology · 2014Review
- OsHUS1 facilitates accurate meiotic recombination in rice.PLoS genetics · 2014Article
- Effect of nuclear architecture on the efficiency of double-strand break repair.Nature cell biology · 2013Article
- Multiple opposing constraints govern chromosome interactions during meiosis.PLoS genetics · 2013Article
- Diversity and recombination of dispersed ribosomal DNA and protein coding genes in microsporidia.PloS one · 2013Article
- Multiple pathways suppress non-allelic homologous recombination during meiosis in Saccharomyces cerevisiae.PloS one · 2013Article
- Sequencing of pooled DNA samples (Pool-Seq) uncovers complex dynamics of transposable element insertions in Drosophila melanogaster.PLoS genetics · 2012Article
- Modeling meiotic chromosomes indicates a size dependent contribution of telomere clustering and chromosome rigidity to homologue juxtaposition.PLoS computational biology · 2012Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To examine constrains imposed on meiotic recombination by homologue pairing, we measured the frequency of recombination between mutant alleles of the ARG4 gene contained in pBR322-based inserts. Inserts were located at identical loci on homologues (allelic recombination) or at different loci on either homologous or heterologous chromosomes (ectopic recombination). Ectopic recombination between interstitially located inserts on heterologous chromosomes had an efficiency of 6-12% compared to allelic recombination. By contrast, ectopic recombination between interstitial inserts located on homologues had relative efficiencies of 47-99%. These findings suggest that when meiotic ectopic recombination occurs, homologous chromosomes are already colocalized. The efficiency of ectopic recombination between inserts on homologues decreased as the physical distance between insert sites was increased. This result is consistent with the suggestion that during meiotic recombination, homologues are not only close to each other, but also are aligned end to end. Finally, the efficiency of ectopic recombination between inserts near telomeres (within 16 kb) was significantly greater than that observed with inserts > 50 kb from the nearest telomere. Thus, at the time of recombination, there may be a special relationship between the ends of chromosomes not shared with interstitial regions.
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