ArticleMolecules (Basel, Switzerland)2026
Comparative Antioxidant Profiling of Phenolic Acids and Flavonoids: Assay-Resolved Structure-Activity Relationships Under Harmonized In Vitro Conditions.
Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Phytochemical Characterization and Antioxidant Mechanisms of Amazonian Tucumã (Astrocaryum vulgare) and Uxi (Endopleura uchi) Pulps Support Their Potential as Natural Food Preservatives.Journal of food science · 2026Article
- Antioxidant Activity and HepG2 Cytoprotection of Water-Soluble Chili Pepper Polyphenols.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026Article
- Assay-Dependent Variability of Antioxidant Responses in Hop Extracts: Implications for Cross-Study Comparability and Antioxidant Interpretation.Molecules (Basel, Switzerland) · 2026Article
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5 authors.
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Abstract
Phenolic acids and flavonoids remain attractive redox-active scaffolds in medicinal chemistry, where they are widely used for early-stage prioritization and intrinsic reactivity ranking. However, direct comparisons under harmonized conditions remain scarce, limiting structure-based assessment. Here, a structurally diverse panel of hydroxybenzoic acids, hydroxycinnamic acids, flavonoids, a flavanone, and synthetic comparators was profiled using Folin-Ciocalteu response, ABTS radical cation scavenging, DPPH radical scavenging, and reducing power assays. The data reveal pronounced assay dependence alongside clear structure-activity trends. Gallic acid showed the strongest DPPH scavenging (half-maximal inhibitory concentration, IC
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