Evidence map›Paper›PMID 41221374›Full record

ArticleInternational journal of food science2025

Comparisons of the Effects of Low- or High-Fat Diets Rich in Soybean Oil, Lard, and Tea Seed Oil on Markers of Blood-Brain Barrier and Neuroinflammation in Ovariectomized Mice.

Shyh-Hsiang Lin, Cicilia Giofani Soetanto, Wan-Chun Chiu, Tzu-Wen L Cross, Ning-Jo Kao, Yih-Ru Wu, Ching-I Lin, Poulami Jha

Abstract read
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In one paragraph

Article in International journal of food science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shyh-Hsiang LinSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan, tmu.edu.tw.ORCID https://orcid.org/0000-0002-3723-560X
Cicilia Giofani SoetantoSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan, tmu.edu.tw.
Wan-Chun ChiuSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan, tmu.edu.tw.
Tzu-Wen L CrossDepartment of Nutrition Science, Purdue University, West Lafayette, Indiana, USA, purdue.edu.
Ning-Jo KaoDepartment of Nutrition and Health Sciences, Kainan University, Taoyuan, Taiwan, knu.edu.tw.
Yih-Ru WuDepartment of Neurology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, cgmh.org.tw.
Ching-I LinResearch Center for Food and Cosmetic Safety, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan, Taiwan, cgust.edu.tw.ORCID https://orcid.org/0000-0002-1466-9739
Poulami JhaSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan, tmu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-fat diets (HFDs) may affect the blood-brain barrier (BBB) function and cause neuroinflammation. Different dietary oils may influence BBB and neuroinflammatory responses due to their unique fatty acid compositions. To elucidate the potential effects of different dietary oils, this study compared the effects of tea seed oil with those of soybean oil and lard on markers of BBB and neuroinflammation. Six-week-old ovariectomized mice were fed a normal or HFD for 12 weeks. The mice's brain lipid profiles, brain-derived neurotrophic factor (BDNF), BBB function-related markers (i.e., S100 calcium-binding protein

Indexed as

BDNFblood–brain barrierlardneuroinflammationsoybeantea seed oil

Identifiers

PMID41221374
PMCPMC12598498

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.