Evidence map›Paper›PMID 40868713›Full record

ReviewGels (Basel, Switzerland)2025

Machine Learning in Gel-Based Additive Manufacturing: From Material Design to Process Optimization.

Zhizhou Zhang, Yaxin Wang, Weiguang Wang

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Construction of ZnGels (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhizhou ZhangDepartment of Mechanical and Aerospace Engineering, School of Engineering, The University of Manchester, Manchester M13 9PL, UK.
Yaxin WangCentre for the Cellular Microenvironment (CeMi), University of Glasgow, Glasgow G12 8QQ, UK.
Weiguang WangDepartment of Mechanical Engineering, School of Engineering, University of Southampton, Southampton SO17 1BJ, UK.ORCID 0000-0002-8959-329X

Funding

Henry Royce Institute EP/R00661X/1Rosetrees Trust UK CF-2023-I-2\103
6 · The paper itself

Abstract

Machine learning is reshaping gel-based additive manufacturing by enabling accelerated material design and predictive process optimization. This review provides a comprehensive overview of recent progress in applying machine learning across gel formulation development, printability prediction, and real-time process control. The integration of algorithms such as neural networks, random forests, and support vector machines allows accurate modeling of gel properties, including rheology, elasticity, swelling, and viscoelasticity, from compositional and processing data. Advances in data-driven formulation and closed-loop robotics are moving gel printing from trial and error toward autonomous and efficient material discovery. Despite these advances, challenges remain regarding data sparsity, model robustness, and integration with commercial printing systems. The review results highlight the value of open-source datasets, standardized protocols, and robust validation practices to ensure reproducibility and reliability in both research and clinical environments. Looking ahead, combining multimodal sensing, generative design, and automated experimentation will further accelerate discoveries and enable new possibilities in tissue engineering, biomedical devices, soft robotics, and sustainable materials manufacturing.

Indexed as

gels additive manufacturingmachine learningmaterial designprocess optimization

Identifiers

PMID40868713
PMCPMC12385932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.