Evidence map›Paper›PMID 40823029›Full record

SynthesisFrontiers in nutrition2025

Grape pomace as a natural source of antimicrobial agents for food preservation.

Micaela Galante, María Emilia Brassesco, Carollyne Maragoni Santos, Carolina Beres, Ana Elizabeth Cavalcante Fai, Ignacio Cabezudo

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Micaela GalanteLaboratorio de Investigación, Desarrollo y Evaluación de Alimentos (LIDEA), Facultad de Ciencias Bioquímicas y Farmacéuticas (FBioyF), Universidad Nacional de Rosario (UNR) y Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Rosario, Argentina.
María Emilia BrassescoUniversidade Católica Portuguesa, CBQF - Centro de Biotecnologia e Química Fina - Laboratório Associado, Escola Superior de Biotecnologia, Rua Diogo Botelho, Porto, Portugal.
Carollyne Maragoni SantosFood and Nutrition Graduate Program, Federal University of Rio de Janeiro State (UNIRIO), Rio de Janeiro, Brazil.
Carolina BeresDepartment of Basic and Experimental Nutrition, Institute of Nutrition, Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.
Ana Elizabeth Cavalcante FaiFood and Nutrition Graduate Program, Federal University of Rio de Janeiro State (UNIRIO), Rio de Janeiro, Brazil.
Ignacio CabezudoFarmacognosia, FBioyF, UNR y CONICET, Rosario, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Grape pomace, a by-product of winemaking, has emerged as a promising source of natural antimicrobial compounds for food applications. In response to increasing concerns regarding foodborne illnesses and consumer demand for clean-label products, its valorization represents a sustainable approach to enhance food safety and shelf life. This review combines a bibliometric analysis with a critical examination of the scientific literature. The bibliometric analysis identifies leading authors, institutions, countries, and research trends related to the use of grape pomace in food preservation. The literature review summarizes extraction techniques and antimicrobial evaluations. Grape pomace is rich in phenolic compounds with demonstrated antibacterial and antifungal activity. The antimicrobial effectiveness depends on factors such as grape variety, extraction method, polyphenol profile, and target microorganisms. Its incorporation into food productsincluding meat, dairy, and beverageshas shown promising results. Additionally, bioactive extracts have been applied in edible films, coatings, and active packaging to inhibit microbial growth and prolong shelf life. The evidence supports the potential of grape pomace as an effective antimicrobial food additive. However, challenges remain, including the need for standardized extraction protocols, deeper understanding of antimicrobial mechanisms, and comprehensive safety and efficacy evaluations in real food systems. Addressing these gaps is essential to facilitate the development of innovative food preservation strategies based on grape pomace bioactives.

Indexed as

antimicrobial activityclean labelfoodborne pathogensgrape by-productsphenolic compounds

Identifiers

PMID40823029
PMCPMC12354373

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.