Evidence map›Paper›PMID 40451934›Full record

ArticleScientific reports2025

Functional metabolites and inhibitory efficacy of kombucha beverage on pathogenic bacteria, free radicals and inflammation.

Nitsanat Cheepchirasuk, Thida Kaewkod, Sureeporn Suriyaprom, Varachaya Intachaisri, Pornpimon Ngamsaard, Yingmanee Tragoolpua

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nitsanat CheepchirasukDoctor of Philosophy Program in Applied Microbiology (International Program), Faculty of Science, Chiang Mai University, Chiang Mai, Thailand.
Thida KaewkodDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Sureeporn SuriyapromDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Varachaya IntachaisriDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Pornpimon NgamsaardDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Yingmanee TragoolpuaDepartment of Biology, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand. yingmanee.t@cmu.ac.th.

Funding

National Research Council of Thailand (NRCT) and Research and Researchers for Industrial (RRI) Fund N23G660002
6 · The paper itself

Abstract

Kombucha tea is a fermented tea that produced by acetic acid bacteria and yeast. In this study, the kombucha tea from white, green and black tea was studied for its microbial composition, chemical profile, and biological activities during 15-day fermentation period. HPLC analysis revealed key organic acids, including acetic, gluconic, and glucuronic acids in kombucha tea.  In this study, white tea kombucha showed the highest glucuronic acid content. Green tea kombucha demonstrated the highest antioxidant activity by ABTS and FRAP assays. Moreover, white tea kombucha exhibited the strongest DPPH scavenging activity and high phenolic content. Additionally, kombucha tea could inhibit the growth of pathogenic bacteria, including Escherichia coli, E. coli O157:H7, Salmonella Typhi, Shigella dysenteriae, and Vibrio cholerae. Furthermore, green tea kombucha significantly inhibited nitric oxide production on LPS-stimulated RAW264.7 cells and demonstrated the strongest anti-inflammatory effect. These findings highlight a potential of kombucha tea as a functional beverage with antioxidant, antibacterial, and anti-inflammatory properties.

Indexed as

Anti-Bacterial AgentsAnti-Inflammatory AgentsBacteriaInflammationKombucha TeaAnimalsAntioxidantsFree RadicalsMiceNitric OxidePhenolsPlant ExtractsRAW 264.7 CellsTeaAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsFree RadicalsKombucha TeaNitric OxidePhenolsPlant ExtractsTeaAnti-inflammatoryAntioxidationFermentationKombucha teaPathogenic bacteria

Identifiers

PMID40451934
PMCPMC12127459

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.