Evidence map›Paper›PMID 40422801›Full record

ReviewMarine drugs2025

Deep Eutectic Systems: A Game Changer for Marine Bioactives Recovery.

Sandro Amador, Alice Martins, Margarida Matias, Rui Pedrosa, Susete Pinteus

Abstract readReview
In one paragraph

Review in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sandro AmadorInstituto de Tecnologia Química e Biológica António Xavier (ITQB), NOVA University of Lisbon, Av. da República, 2780-157 Oeiras, Portugal.ORCID 0009-0001-4726-8122
Alice MartinsMARE-Marine and Environmental Sciences Centre/ARNET-Aquatic Research Network, ESTM, Polytechnic University of Leiria, 2520-630 Peniche, Portugal.
Margarida MatiasMARE-Marine and Environmental Sciences Centre/ARNET-Aquatic Research Network, ESTM, Polytechnic University of Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0002-8866-2564
Rui PedrosaMARE-Marine and Environmental Sciences Centre/ARNET-Aquatic Research Network, ESTM, Polytechnic University of Leiria, 2520-630 Peniche, Portugal.
Susete PinteusMARE-Marine and Environmental Sciences Centre/ARNET-Aquatic Research Network, ESTM, Polytechnic University of Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0002-3290-3111

Funding

Fundação para a Ciência e Tecnologia 2023.06631.CEECIND.Fundação para a Ciência e Tecnologia DOI 10.54499/UIDP/04292/2020; DOI 10.54499/UIDB/04292/2020; DOI 10.54499/LA/P/0069/2020;https://doi.org/10.54499/2023.13029.PEXInterreg Atlantic Area and co-funded by the European project BEAP-MAR (EAPA 0032/2022-Blue Bioeconomy in the Atlantic Area: New Products from Marine Organisms)la Caixa Foundation LCF/TR/CI23/56000027
6 · The paper itself

Abstract

The extraction of bioactive compounds from marine natural products has gained increasing attention due to their diverse applications, such as in pharmaceuticals, nutraceuticals, and cosmetics. Yet, low extraction yields and toxicity associated with common solvents are a major bottleneck. Deep eutectic solvents (DESs) and natural deep eutectic solvents (NADESs) have emerged as promising green alternatives to conventional organic solvents, offering advantages such as biodegradability, greater environmental and economic sustainability, low toxicity, and enhanced extraction selectivity. This review provides a comprehensive analysis of the principles, physicochemical properties, and applications of DESs/NADESs to obtain bioactive compounds from marine organisms. Among the most recent works, it is possible to verify the success of NADESs to extract carrageenan from the seaweed

Indexed as

Aquatic OrganismsBiological ProductsSolventsAnimalsGreen Chemistry TechnologyHumansSeaweedBiological ProductsSolventsblue bioeconomydeep eutectic systemsmarine-derived compoundsnew-generation solventssustainable extraction technologies

Identifiers

PMID40422801
PMCPMC12113362

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.