Evidence map›Paper›PMID 38613086›Full record

ArticleNutrients2024

Is Ultra-Processed Food Intake Associated with a Higher Risk of Glaucoma? A Prospective Cohort Study including 19,255 Participants from the SUN Project.

José Francisco López-Gil, Alejandro Fernandez-Montero, Maira Bes-Rastrollo, Laura Moreno-Galarraga, Stefanos N Kales, Miguel Ángel Martínez-González, Javier Moreno-Montañés

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

José Francisco López-GilOne Health Research Group, Universidad de Las Américas, Quito 170124, Ecuador.ORCID 0000-0002-7412-7624
Alejandro Fernandez-MonteroDepartment of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, MA 02138, USA.ORCID 0000-0002-8741-7401
Maira Bes-RastrolloDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-9139-4206
Laura Moreno-GalarragaInstituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain.ORCID 0000-0003-0293-0749
Stefanos N KalesDepartment of Environmental Health, T.H. Chan School of Public Health, Harvard University, Boston, MA 02138, USA.ORCID 0000-0002-7712-4664
Miguel Ángel Martínez-GonzálezDepartment of Preventive Medicine and Public Health, School of Medicine, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3917-9808
Javier Moreno-MontañésInstituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain.ORCID 0000-0002-6623-6783
Harvard University · USInstituto de Salud Carlos III · ESNavarre Institute of Health Research · ESServicio Navarro de Salud · ESUniversidad de Las Américas · EC

Funding

Gobierno de Navarra (27/2011, 45/2011, 122/2014)Instituto de Salud Carlos III (RD 06/0045, CIBER-OBN, Grants PI10/02658, PI10/02293, PI13/00615, PI14/01668, PI14/01798, PI14/01764, PI17/01795, and G03/140)
6 · The paper itself

Abstract

objectiveThe aim of this study was to examine the relationship of ultra-processed food (UPF) intake with the incidence of glaucoma in a large sample of Spanish university graduates followed prospectively.

methodsProspective cohort study using data from the SUN Project. A final sample of 19,225 participants (60.1% women) was included in this study, with a mean age of 38.2 years (standard deviation (SD) = 12.4). Participants were followed-up for a mean time of 12.9 years (SD = 5.4). Dietary intake was measured using a 136-item semiquantitative food-frequency questionnaire. UPFs were defined based on the NOVA classification system. Glaucoma diagnosis was determined by asking the participants if they had ever been diagnosed with glaucoma by an ophthalmologist. This self-reported diagnosis of glaucoma has been previously validated.

resultsAfter adjusting for several covariates, participants with the highest UPF consumption were at higher risk of glaucoma (hazard ratio (HR) = 1.83; 95% confidence interval (CI) 1.06 to 3.17) when compared to participants in the lowest category of UPF consumption. Regarding subgroup analyses, a significant multiplicative interaction was found for age (

conclusionsThis prospective cohort study shows that participants with a greater UPF consumption have a higher risk of developing glaucoma when compared to participants with a lower consumption. Our findings emphasize the relevance of monitoring and limiting the consumption of UPFs as a means of preventing glaucoma incidence.

Indexed as

Fatty Acids, Omega-3GlaucomaAdultAgedCandyEnergy IntakeFemaleFood, ProcessedHumansMaleProspective StudiesFatty Acids, Omega-3eating healthyeye diseasesglaucomaMediterranean cohortNOVA food classification system

Identifiers

PMID38613086
PMCPMC11013077
OpenAlexW4393934893

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.