Evidence map›Paper›PMID 38135651›Full record

ArticleOrganic letters2024

Rational Design and Synthesis of an Artificial Enzyme for S

Foroogh Bahrami, Yan Zhao

Open access · greenAbstract read
In one paragraph

Article in Organic letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Foroogh BahramiDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, United States.
Yan ZhaoDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, United States.ORCID 0000-0003-1215-2565
Iowa State University · US

Funding

Artificial Glycosidase with Controlled SelectivityR01GM138427 · NIGMS · IOWA STATE UNIVERSITY · PI ZHAO, YAN · 2020 to 2023
$1.3M
NIGMS NIH HHS R01 GM138427
6 · The paper itself

Abstract

The rational design of catalysts with enzyme-like properties is an elusive goal of chemists despite tremendous interest. Molecular imprinting inside surfactant micelles, followed by postmodification, creates a tailored active site in a water-soluble polymeric "artificial enzyme" for the benzylation of 4-nitrophenol. The reaction happens under neutral conditions with excellent substrate selectivity. Similar to many enzymes, electrostatics play vital roles in catalysis and can be tuned through different bases introduced into the active site.

Indexed as

EnzymesMicellesMolecular ImprintingNitrophenolsBenzyl CompoundsCatalysisCatalytic DomainSurface-Active AgentsWater4-nitrophenolBenzyl CompoundsEnzymesMicellesNitrophenolsSurface-Active AgentsWater

Identifiers

PMID38135651
PMCPMC11097202
OpenAlexW4390125331

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.