ReviewFrontiers in endocrinology2023
Sarcopenic obesity: epidemiology, pathophysiology, cardiovascular disease, mortality, and management.
Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 172 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
172 citing papers in PubMed, 12 syntheses or guidelines pooled it, 229 citations in OpenAlex.
- Systematic review and meta-analysis of biomarkers of sarcopenia and sarcopenic obesity.Medicine · 2026Pooled it
- Effect of GLP-1 receptor agonists at doses for obesity management on muscle health: systematic review and meta-analysis of randomized controlled trials (RCTs).International journal of obesity (2005) · 2026 · on this mapPooled it
- Dietary Strategies and Nutritional Management in Patients Receiving GLP-1 and Dual GIP/GLP-1 Receptor Agonists as Adjuncts to Lifestyle Interventions: A Systematic Review of Randomised Clinical Trials.Diabetes, obesity & metabolism · 2026Pooled it
- Exercise-based interventions for sarcopenic obesity in middle-aged and older adults: an umbrella review of systematic reviews with pairwise meta-analyses and network meta-analyses.Frontiers in nutrition · 2026Pooled it
- Prevalence of sarcopenic obesity in adult patients with diabetes and associated factors: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Comparative effectiveness and dose-response relationship of exercise-based interventions for muscle mass in older women with sarcopenia: a systematic review and network meta-analysis.Frontiers in medicine · 2026Pooled it
- Effect of adipose-related parameters on mortality in patients with liver cirrhosis: a meta-analysis.Annals of medicine · 2025Pooled it
- Pooled it
- Association of sarcopenic obesity with cognitive dysfunction and dementia: a systematic review and meta-analysis.Aging clinical and experimental research · 2025Pooled it
- Association of sarcopenic obesity with cognitive dysfunction: A systematic review and meta-analysis.Neurosciences (Riyadh, Saudi Arabia) · 2025Pooled it
- Genetic Patterns Related with the Development and Progression of Sarcopenia and Sarcopenic Obesity: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- The Role of Vitamin D Supplementation in Enhancing Muscle Strength Post-Surgery: A Systemic Review.Nutrients · 2025Pooled it
- Effect of a 16-Week Exercise Program After Bariatric Surgery on Sarcopenia Parameters Based on FNIH, EWGSOP2, and EASO/ESPEN Criteria: the Results of the EXPOBAR Randomized Trial Program.Obesity surgery · 2025Trial
- Efficacy of Power Training on Sarcopenic Obesity in Community-Dwelling Older Women: A 32-Week Randomized Clinical Trial.Nutrients · 2025Trial
- Trial
- Endocrinological aspects of sarcopenic obesity.Annals of medicine · 2026Review
- Indices of obesity, malnutrition and inflammation are strong predictors of mortality in adults with type 2 diabetes: the FIELD study.Diabetologia · 2026Article
- Obesity Attenuates the Association Between the Modified Five-Item Frailty Score and Mortality in Septic Surgical Patients.The Journal of surgical research · 2026Article
- Aerobic Exercise Attenuates High-Fat Diet-Induced Skeletal Muscle Atrophy by Suppressing Oxidative Stress, Inflammation, and Drp1-Associated Mitochondrial Fission.Antioxidants (Basel, Switzerland) · 2026Article
- Association Between Oral Frailty and Body Mass Index in Late-Stage Older Adults Stratified by Sarcopenia Status.Nutrients · 2026Article
112 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sarcopenic obesity is defined as the coexistence of sarcopenia and obesity in the same individual, characterized by of the co-presence of body fat accumulation and muscle loss. This condition is currently a major concern as it is associated with frailty and disabilities such as cardiovascular disease, fractures, dementia, cancer, and increased all-cause mortality. Particularly, older individuals remain at risk of sarcopenic obesity. Progress at several levels is needed to improve the global prognostic outlook for this condition, including the elaboration and implementation of a more uniform definition that may favor the identification and specification of prevalence by age group. Furthermore, improvements in the understanding of the pathogenesis of sarcopenic obesity may lead to the development of more specific therapeutic interventions to improve prognosis. We reviewed the knowledge on sarcopenic obesity and its associations with cardiovascular diseases and mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.