Evidence map›Paper›PMID 36986239›Full record

ReviewNutrients2023

Alternative Protein Sources and Novel Foods: Benefits, Food Applications and Safety Issues.

Laura Quintieri, Chiara Nitride, Elisabetta De Angelis, Antonella Lamonaca, Rosa Pilolli, Francesco Russo, Linda Monaci

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
31.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
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  5. Article
  6. Article
  7. In vivo mammalian micronucleus test in mice confirms lack of genotoxic potential of a protein-rich powder derived from Xanthobacter sp. SoF1.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Impact of dietary supplementation of black soldier fly larvae (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025
    Article
  15. Review
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Laura QuintieriInstitute of Sciences of Food Production, National Research Council of Italy (ISPA-CNR), Via Giovanni Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0001-6261-9544
Chiara NitrideDepartment of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici, Italy.ORCID 0000-0003-3587-6187
Elisabetta De AngelisInstitute of Sciences of Food Production, National Research Council of Italy (ISPA-CNR), Via Giovanni Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0003-1290-4544
Antonella LamonacaInstitute of Sciences of Food Production, National Research Council of Italy (ISPA-CNR), Via Giovanni Amendola 122/O, 70126 Bari, Italy.
Rosa PilolliInstitute of Sciences of Food Production, National Research Council of Italy (ISPA-CNR), Via Giovanni Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0002-6789-1472
Francesco RussoFunctional Gastrointestinal Disorders Research Group, National Institute of Gastroenterology IRCCS "Saverio de Bellis", 70013 Castellana Grotte, Italy.ORCID 0000-0003-0538-6072
Linda MonaciInstitute of Sciences of Food Production, National Research Council of Italy (ISPA-CNR), Via Giovanni Amendola 122/O, 70126 Bari, Italy.ORCID 0000-0001-5650-7909
Institute of Sciences of Food Production · ITGastroenterology Hospital "Saverio de Bellis" · ITUniversity of Naples Federico II · IT

Funding

Alifun Project "Sviluppo di ALImenti FUNzionali per l'innovazione dei prodotti alimentari di tradizione italiana - Italian PON PON ARS01_00783EITFood Nutribox 20431-21
6 · The paper itself

Abstract

The increasing size of the human population and the shortage of highly valuable proteinaceous ingredients has prompted the international community to scout for new, sustainable, and natural protein resources from invertebrates (e.g., insects) and underutilized legume crops, unexploited terrestrial and aquatic weeds, and fungi. Insect proteins are known for their nutritional value, being rich in proteins with a good balance of essential amino acids and being a valuable source of essential fatty acids and trace elements. Unconventional legume crops were found rich in nutritional, phytochemical, and therapeutic properties, showing excellent abilities to survive extreme environmental conditions. This review evaluates the recent state of underutilized legume crops, aquatic weeds, fungi, and insects intended as alternative protein sources, from ingredient production to their incorporation in food products, including their food formulations and the functional characteristics of alternative plant-based proteins and edible insect proteins as novel foods. Emphasis is also placed on safety issues due to the presence of anti-nutritional factors and allergenic proteins in insects and/or underutilized legumes. The functional and biological activities of protein hydrolysates from different protein sources are reviewed, along with bioactive peptides displaying antihypertensive, antioxidant, antidiabetic, and/or antimicrobial activity. Due to the healthy properties of these foods for the high abundance of bioactive peptides and phytochemicals, more consumers are expected to turn to vegetarianism or veganism in the future, and the increasing demand for such products will be a challenge for the future.

Indexed as

AntioxidantsCrops, AgriculturalHumansNutritive ValuePeptidesPlant ProteinsAntioxidantsPeptidesPlant Proteinsalternative proteinsaquatic weedsbioactive peptidesfood formulationfungiinsectsnovel foodsunderutilized legumes

Identifiers

PMID36986239
PMCPMC10054669
OpenAlexW4328127090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.