Evidence map›Paper›PMID 36677615›Full record

ReviewMolecules (Basel, Switzerland)2023

Advances in the Chemistry, Analysis and Adulteration of Anthocyanin Rich-Berries and Fruits: 2000-2022.

Bharathi Avula, Kumar Katragunta, Ahmed G Osman, Zulfiqar Ali, Sebastian John Adams, Amar G Chittiboyina, Ikhlas A Khan

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Structure Elucidation of Purpurinidin fromJournal of natural products · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bharathi AvulaNational Center for Natural Products Research, University, MS 38677, USA.
Kumar KatraguntaNational Center for Natural Products Research, University, MS 38677, USA.ORCID 0000-0002-8787-4602
Ahmed G OsmanNational Center for Natural Products Research, University, MS 38677, USA.
Zulfiqar AliNational Center for Natural Products Research, University, MS 38677, USA.ORCID 0000-0003-3902-5152
Sebastian John AdamsNational Center for Natural Products Research, University, MS 38677, USA.
Amar G ChittiboyinaNational Center for Natural Products Research, University, MS 38677, USA.ORCID 0000-0002-7047-5373
Ikhlas A KhanNational Center for Natural Products Research, University, MS 38677, USA.
University of Mississippi · US

Funding

Science based authentication, validation & safety of botanical ingredientsU01FD004246 · FDA · UNIVERSITY OF MISSISSIPPI · PI Amar G. Chittiboyina, Ikhlas Ahmad Khan · 2011 to 2026
$38.2M
FDA HHS U01 FD004246
6 · The paper itself

Abstract

Anthocyanins are reported to exhibit a wide variety of remedial qualities against many human disorders, including antioxidative stress, anti-inflammatory activity, amelioration of cardiovascular diseases, improvement of cognitive decline, and are touted to protect against neurodegenerative disorders. Anthocyanins are water soluble naturally occurring polyphenols containing sugar moiety and are found abundantly in colored fruits/berries. Various chromatographic (HPLC/HPTLC) and spectroscopic (IR, NMR) techniques as standalone or in hyphenated forms such as LC-MS/LC-NMR are routinely used to gauge the chemical composition and ensure the overall quality of anthocyanins in berries, fruits, and finished products. The major emphasis of the current review is to compile and disseminate various analytical methodologies on characterization, quantification, and chemical profiling of the whole array of anthocyanins in berries, and fruits within the last two decades. In addition, the factors affecting the stability of anthocyanins, including pH, light exposure, solvents, metal ions, and the presence of other substances, such as enzymes and proteins, were addressed. Several sources of anthocyanins, including berries and fruit with their botanical identity and respective yields of anthocyanins, were covered. In addition to chemical characterization, economically motivated adulteration of anthocyanin-rich fruits and berries due to increasing consumer demand will also be the subject of discussion. Finally, the health benefits and the medicinal utilities of anthocyanins were briefly discussed. A literature search was performed using electronic databases from PubMed, Science Direct, SciFinder, and Google Scholar, and the search was conducted covering the period from January 2000 to November 2022.

Indexed as

AnthocyaninsFruitChromatography, High Pressure LiquidHumansMass SpectrometryPolyphenolsAnthocyaninsPolyphenolsanalytical techniquesanthocyaninschemistryfruit and berrieshealth benefitsstability

Identifiers

PMID36677615
PMCPMC9865467
OpenAlexW4313646902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.