Evidence map›Paper›PMID 36660302›Full record

ArticleCurrent research in food science2023

The role of glycosylation in amyloid fibril formation of bovine κ-casein.

Barana Hewa Nadugala, Rick Hantink, Tom Nebl, Jacinta White, Charles N Pagel, C S Ranadheera, Amy Logan, Jared K Raynes

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current research in food science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Barana Hewa NadugalaSchool of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, VIC, 3052, Australia.
Rick HantinkCSIRO Agriculture and Food, Werribee Victoria, 3030, Australia.
Tom NeblBiology Group, Biomedical Manufacturing Program, CSIRO, Bayview Ave/Research Way, Clayton, VIC, 3168, Australia.
Jacinta WhiteCSIRO Manufacturing, Bayview Avenue, Clayton, VIC, 3168, Australia.
Charles N PagelMelbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, VIC, 3052, Australia.
C S RanadheeraSchool of Agriculture and Food, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, VIC, 3052, Australia.
Amy LoganCSIRO Agriculture and Food, Werribee Victoria, 3030, Australia.
Jared K RaynesSchool of Chemical and Biomolecular Engineering, Faculty of Engineering, The University of Sydney, NSW, 2006, Australia.
Commonwealth Scientific and Industrial Research Organisation · AUCSIRO Manufacturing · AUThe University of Melbourne · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to explore the functions of glycosylation of κ-Casein (κ-CN) in bovine milk, unglycosylated (UG) and twice glycosylated (2G) forms of κ-CN B were purified by selective precipitation followed by anion exchange chromatography from κ-CN BB milk and tested for their amyloid fibril formation and morphology, oligomerisation states and protein structure. The diameter of self-assembled κ-CN B aggregates of both glyco-form were shown for the first time to be in the same 26.0-28.7 nm range for a 1 mg mL

Indexed as

Genetic variantGlycanMicelle-like aggregateProtein aggregationSelf-assembled

Identifiers

PMID36660302
PMCPMC9842538
OpenAlexW4313530540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.