Evidence map›Paper›PMID 36615405›Full record

ArticleMolecules (Basel, Switzerland)2022

Antioxidant, Anti-Diabetic, Anti-Obesity, and Antihypertensive Properties of Protein Hydrolysate and Peptide Fractions from Black Sesame Cake.

Supakit Chaipoot, Wanisa Punfa, Sakaewan Ounjaijean, Rewat Phongphisutthinant, Kanokwan Kulprachakarn, Wason Parklak, Laddawan Phaworn, Pattrawan Rotphet, Kongsak Boonyapranai

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Anti-obesity peptides from food: Production, evaluation, sources, and commercialization.Comprehensive reviews in food science and food safety · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Supakit ChaipootScience and Technology Research Institute, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-9817-306X
Wanisa PunfaSchool of Traditional and Alternative Medicine, Chiang Rai Rajabhat University, Chiang Rai 57100, Thailand.
Sakaewan OunjaijeanResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-9067-2051
Rewat PhongphisutthinantScience and Technology Research Institute, Chiang Mai University, Chiang Mai 50200, Thailand.
Kanokwan KulprachakarnResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-2572-0704
Wason ParklakResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Laddawan PhawornFaculty of Allied Health Sciences, Nakhon Ratchasima College, Nakhon Ratchasima 30000, Thailand.
Pattrawan RotphetFaculty of Allied Health Sciences, Nakhon Ratchasima College, Nakhon Ratchasima 30000, Thailand.
Kongsak BoonyapranaiResearch Institute for Health Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-1429-7709
Chiang Mai University · THChiang Rai Rajabhat University · TH

Funding

Thailand Research Fund 71712
6 · The paper itself

Abstract

A low-value by-product of cold-pressed sesame oil is defatted black sesame cake (DBSC). The remaining protein and essential amino acids may be utilized as a renewable biological source to produce bioactive products. The bioactivities of the protein hydrolysate from black sesame cake and its peptide fractions were examined in this study for in vitro antioxidant activity and inhibition of DPP-IV, ACE, α-amylase, α-glucosidase, and pancreatic lipase. By using Flavourzyme to hydrolyze DBSC, followed by ultrafiltration, fractions with peptide sizes of <3, 3−10, and >10 kDa were obtained. According to the findings, the products of DBSC could neutralize free radicals and prevent ferric ion redox reactions. The highest inhibitory effects were shown with low Mw peptides (<3 kDa) against ACE, DPP-IV, α-amylase, and α-glucosidase. DBSC has demonstrated potential as a nutraceutical or functional ingredient for preventing and treating disorders associated with free radicals, such as diabetes, hypertension, and hyperglycemia.

Indexed as

Diabetes MellitusSesamumalpha-Amylasesalpha-GlucosidasesAntihypertensive AgentsAntioxidantsPeptidesProtein Hydrolysatesalpha-Amylasesalpha-GlucosidasesAntihypertensive AgentsAntioxidantsPeptidesProtein Hydrolysatesenzymatic hydrolysisin vitro studymembrane filtrationpeptidesesame

Identifiers

PMID36615405
PMCPMC9821986
OpenAlexW4313245339

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.