Evidence map›Paper›PMID 36531466›Full record

SynthesisFrontiers in endocrinology2022

Circulating and dietary advanced glycation end products and obesity in an adult population: A paradox of their detrimental effects in obesity.

Abduladheem Turki Jalil, Ameer A Alameri, Rumi Iqbal Doewes, Amr A El-Sehrawy, Irfan Ahmad, Pushpamala Ramaiah, Mustafa M Kadhim, Hamzah H Kzar, R Sivaraman, Rosario Mireya Romero-Parra and 2 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Glycative stress as a cause of macular degeneration.Progress in retinal and eye research · 2024
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Receptor for the Advanced Glycation End Products (International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 12 institutions in 6 countries.

Abduladheem Turki JalilMedical Laboratories Techniques Department, Al-Mustaqbal University College, Babylon, Hilla, Iraq.
Ameer A AlameriCollege of Science, University of Babylon, Babylon, Iraq.
Rumi Iqbal DoewesFaculty of Sport, Universitas Sebelas Maret, Surakarta, Indonesia.
Amr A El-SehrawyDepartment of Internal Medicine, Faculty of Medicine, Mansoura Specialized Medical Hospital, Mansoura University, Mansoura, Egypt.
Irfan AhmadDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Pushpamala RamaiahFaculty of Nursing, Umm al- Qura University, Makkah, Saudi Arabia.
Mustafa M KadhimMedical Laboratory Techniques Department, Al-Farahidi University, Baghdad, Iraq.
Hamzah H KzarVeterinary Medicine College, Al-Qasim Green University, Al-Qasim, Iraq.
R SivaramanDepartment of Mathematics, Dwaraka Doss Goverdhan Doss Vaishnav College, Arumbakkam, University of Madras, Chennai, India.
Rosario Mireya Romero-ParraDepartment of General Studies, Universidad Continental, Lima, Peru.
Mohammad Javed AnsariDepartment of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-kharj, Saudi Arabia.
Yasser Fakri MustafaDepartment of Pharmaceutical Chemistry, College of Pharmacy, University of Mosul, Mosul, Iraq.
Al-Farahidi UniversityAlsalam University College · IQKing Khalid University · SAMansoura University · EGMinistry of Higher Education and Scientific Research · IQPrince Sattam Bin Abdulaziz University · SASebelas Maret University · IDUmm al-Qura University · SAUniversidad Continental · PEUniversity of Babylon · IQUniversity of Madras · INUniversity of Mosul · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The detrimental role of advanced glycation end products (AGEs) against cardio-metabolic health has been revealed in several previous reports. However, the results of studies regarding the association between AGEs and obesity measurements are inconsistent. In the current meta-analysis, we aimed to quantitatively summarize the results of studies that evaluated the association between circulating and dietary AGEs with obesity measurements among the adult population. Methods: A systematic search from PubMed, Embase, and Scopus electronic databases until 30 October 2022 retrieved a total of 21,429 observational studies. After duplicate removal, title/abstract screening, and full-text reading by two independent researchers, a final number of 18 manuscripts remained to be included in the meta-analysis. Results: Those in the highest category of circulating AGEs had ~1.5 kg/m Conclusion: In the current meta-analysis, we observed an inverse association between circulating AGEs and body mass index among adults. Due to low study numbers, further studies are warranted to better elucidate these results.

Indexed as

Dietary Advanced Glycation End ProductsGlycation End Products, AdvancedAdultBody Mass IndexHumansObesityDietary Advanced Glycation End ProductsGlycation End Products, AdvancedAGEsBMI - body mass indexcardiovascular diseaseobesitysRAGE level

Identifiers

PMID36531466
PMCPMC9752071
OpenAlexW4311065935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.