Evidence map›Paper›PMID 36501149›Full record

ArticleNutrients2022

Cognitive Impairment Mediates the Association between Dietary Inflammation and Depressive Symptoms in the Elderly.

Mengzi Sun, Ling Wang, Yueyang Hu, Xuhan Wang, Shoumeng Yan, Yinpei Guo, Jing Li, Zechun Xie, Bo Li

Abstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mengzi SunDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.ORCID 0000-0001-8001-8064
Ling WangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Yueyang HuDepartment of Social Medicine and Health Management, School of Public Health, Jilin University, Changchun 130012, China.
Xuhan WangDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Shoumeng YanSchool of Nursing, Jilin University, Changchun 130021, China.
Yinpei GuoDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Jing LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Zechun XieDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.
Bo LiDepartment of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun 130021, China.ORCID 0000-0003-1455-9596

Funding

National Natural Science Foundation of China 81973129
6 · The paper itself

Abstract

The underlying mechanism in both cognitive impairment and depression was chronic inflammation, which could be reflected by the dietary inflammatory index (DII). However, the effect of cognitive impairment on the association between DII and depression was not clear. Therefore, in this study, we hypothesized that cognitive impairment could mediate the association between dietary inflammation and depressive symptoms. A total of 2550 participants aged ≥60 from the National Health and Nutrition Examination Survey (NHANES) in 2011-2014 were involved in the serial, cross-sectional study. Proinflammatory and anti-inflammatory diets were measured by DII. Cognitive impairment was measured by four dimensions, CERAD-immediate, CERAN-delayed, animal fluency test, and DSST. Depressive symptoms were measured by PHQ-9 scores. We found that a proinflammatory diet and cognitive impairment were both risk factors for depressive symptoms. An interaction between an inflammatory diet and cognitive impairment was detected (

Indexed as

Cognitive DysfunctionDietCross-Sectional StudiesHumansInflammationNutrition Surveyscognitive functiondepressive symptomsdietary inflammatory indexmediation

Identifiers

PMID36501149
PMCPMC9737219

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.