ArticleAntioxidants (Basel, Switzerland)2022
Bioaccessibility of Phenolic Compounds and Antioxidant Properties of Goat-Milk Powder Fortified with Grape-Pomace-Seed Extract after In Vitro Gastrointestinal Digestion.
Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- α- and β-Casein Differentially Protect Anthocyanins from Three Red Grape (Foods (Basel, Switzerland) · 2026Article
- Development of Skimmed Goat Milk Functional Ingredient Enriched with Grape Pomace Seed andFoods (Basel, Switzerland) · 2026Article
- Gastrointestinal Digestion Impact on Phenolics and Bioactivity of Tannat Grape Pomace Biscuits.Molecules (Basel, Switzerland) · 2025Article
- The Bioaccessibility of Grape-Derived Phenolic Compounds: An Overview.Foods (Basel, Switzerland) · 2025Review
- Modulation of Gut Microbiota Composition and Microbial Phenolic Catabolism of Phenolic Compounds fromJournal of agricultural and food chemistry · 2025Article
- Goat's Milk Powder Enriched with Red (Foods (Basel, Switzerland) · 2024Article
- Improving oxidative stability of cream powder using pomegranate concentrate and peel extract.Food science & nutrition · 2024Article
- Therapeutic effect of goat milk and its value-addition: current status and way forward.Journal of food science and technology · 2024Review
- Phytochemical Analysis, Biological Activities, and Molecular Docking Studies of Root Extracts fromPharmaceuticals (Basel, Switzerland) · 2024Article
- Bioaccessibility and antioxidant capacity of kefir-based smoothies fortified with kale and spinach after in vitro gastrointestinal digestion.Food science & nutrition · 2024Article
- Antioxidant Properties of Bioactive Compounds in Fruit and Vegetable Waste.Antioxidants (Basel, Switzerland) · 2023Article
- Okara-Enriched Gluten-Free Bread: Nutritional, Antioxidant and Sensory Properties.Molecules (Basel, Switzerland) · 2023Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
This study deals with the evaluation of the bioaccessibility and antioxidant properties of phenolic compounds from heat-treated skim goat-milk powder fortified with grape-pomace-seed extract, after in vitro gastrointestinal digestion. Ultra-high performance liquid chromatography coupled to diode array detection and mass spectrometry (UHPLC-DAD MS/MS) analysis confirmed the abundant presence of phenolic acids and flavan-3-ols in the grape-pomace-seed extract (SE) and heat-treated skim goat-milk/seed-extract powder (TME). After in vitro digestion of TME powder and recovery of total quantified phenolics, flavan-3-ols and phenolic acids were 18.11%, 24.54%, and 1.17%, respectively. Low recovery of grape-pomace-seed phenolics indicated strong milk protein-phenolic interactions. Electrophoretic analysis of a soluble fraction of digested heat-treated skim goat milk (TM) and TME samples showed the absence of bands originating from milk proteins, indicating their hydrolysis during in vitro gastrointestinal digestion. The digested TME sample had better antioxidant properties in comparison to the digested TM sample (except for the ferrous ion-chelating capacity, FCC), due to the presence of bioaccessible phenolics. Taking into account the contribution of the digestive cocktail, digested TME sample had lower values of total phenolic content (TPC), in vitro phosphomolybdenum reducing capacity (TAC) and ferric reducing power (FRP), compared to the undigested TME sample. These results could be attributed to low recovery of phenolic compounds. TME powder could be a good carrier of phenolics to the colon; thus, TME powder could be a promising ingredient in the formulation of functional food.
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Registered trials
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