Evidence map›Paper›PMID 36245539›Full record

ReviewFrontiers in nutrition2022

Zein-based nano-delivery systems for encapsulation and protection of hydrophobic bioactives: A review.

Xiaojia Yan, Moting Li, Xingfeng Xu, Xuebo Liu, Fuguo Liu

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  8. Preparation and Characterization ofMolecules (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaojia YanCollege of Food Science and Engineering, Northwest A&F University, Xianyang, China.
Moting LiCollege of Food Science and Engineering, Northwest A&F University, Xianyang, China.
Xingfeng XuCollege of Food Science and Engineering, Qingdao Agricultural University, Qingdao, China.
Xuebo LiuCollege of Food Science and Engineering, Northwest A&F University, Xianyang, China.
Fuguo LiuCollege of Food Science and Engineering, Northwest A&F University, Xianyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zein is a kind of excellent carrier materials to construct nano-sized delivery systems for hydrophobic bioactives, owing to its unique interfacial behavior, such as self-assembly and packing into nanoparticles. In this article, the chemical basis and preparation methods of zein nanoparticles are firstly reviewed, including chemical crosslinking, emulsification/solvent evaporation, antisolvent, pH-driven method, etc., as well as the pros and cons of different preparation methods. Various strategies to improve their physicochemical properties are then summarized. Lastly, the encapsulation and protection effects of zein-based nano-sized delivery systems (e.g., nanoparticles, nanofibers, nanomicelles and nanogels) are discussed, using curcumin as a model bioactive ingredient. This review will provide guidance for the in-depth development of hydrophobic bioactives formulations and improve the application value of zein in the food industry.

Indexed as

curcumindeliverynanoparticleself-assemblyzein

Identifiers

PMID36245539
PMCPMC9554640

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.