Evidence map›Paper›PMID 36140956›Full record

ArticleFoods (Basel, Switzerland)2022

Preparation and Characterization of Rutin-Loaded Zein-Carboxymethyl Starch Nanoparticles.

Cuicui Li, Long Chen, David Julian McClements, Xinwen Peng, Chao Qiu, Jie Long, Hangyan Ji, Jianwei Zhao, Xing Zhou, Zhengyu Jin

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cuicui LiSchool of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.
Long ChenSchool of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.ORCID 0000-0002-7218-2283
David Julian McClementsDepartment of Food Science, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0002-9016-1291
Xinwen PengState Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, China.
Chao QiuSchool of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.ORCID 0000-0002-6427-6124
Jie LongSchool of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.
Hangyan JiSchool of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.
Jianwei ZhaoSchool of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.
Xing ZhouSchool of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.
Zhengyu JinSchool of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.

Funding

Natural Science Foundation of Jiangsu Province - China BK20200617the Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University 2022-1-1the National Natural Science Foundation of China No. 32101990
6 · The paper itself

Abstract

In this work, rutin (RT)-loaded zein-carboxymethyl starch (CMS) nanoparticles were successfully prepared by the antisolvent precipitation method. The effect of CMS on composite nanoparticles at different concentrations was studied. When the ratio of zein-RT-CMS was 10:1:30, the encapsulation efficiency (EE) was the highest, reaching 73.5%. At this ratio, the size of the composite nanoparticles was 196.47 nm, and the PDI was 0.13, showing excellent dispersibility. The results of fluorescence spectroscopy, FTIR, XRD, and CD showed that electrostatic interaction, hydrogen bonding, and hydrophobic interaction were the main driving forces for the formation of nanoparticles. It can be seen from the FE-SEM images that the zein-RT-CMS nanoparticles were spherical. With the increase in the CMS concentration, the particles gradually embedded in the cross-linked network of CMS (10:1:50). After RT was loaded on zein-CMS nanoparticles, the thermal stability and pH stability of RT were improved. The results showed that zein-CMS was an excellent encapsulation material for bioactive substances.

Indexed as

carboxymethyl starchformation mechanisminteractionnanoparticlerutinzein

Identifiers

PMID36140956
PMCPMC9497753

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.