Evidence map›Paper›PMID 35970981›Full record

ArticleScientific reports2022

Antibiotic resistance genes of public health importance in livestock and humans in an informal urban community in Nepal.

Cristin C W Young, Dibesh Karmacharya, Manisha Bista, Ajay N Sharma, Tracey Goldstein, Jonna A K Mazet, Christine K Johnson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. Genomic profiling of ESBL/AmpC-producingFrontiers in microbiology · 2026
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  9. Review
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  12. Carbapenem Resistance inBioMed research international · 2024
    Article
  13. Article
  14. Article
  15. Antimicrobial Resistance ofAntibiotics (Basel, Switzerland) · 2023
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Cristin C W YoungEpiCenter for Disease Dynamics, School of Veterinary Medicine, University of California, Davis, 1089 Veterinary Medicine Drive, Davis, CA, 95616, USA.
Dibesh KarmacharyaCenter for Molecular Dynamics, Nepal (CMDN), Thapathali Road 11, Kathmandu, 44600, Nepal. dibesh@cmdn.org.
Manisha BistaMott MacDonald, Noida, Uttar Pradesh, India.
Ajay N SharmaCenter for Molecular Dynamics, Nepal (CMDN), Thapathali Road 11, Kathmandu, 44600, Nepal.
Tracey GoldsteinOne Health Institute, School of Veterinary Medicine, University of California, Davis, CA, USA.ORCID 0000-0002-1672-7410
Jonna A K MazetOne Health Institute, School of Veterinary Medicine, University of California, Davis, CA, USA.
Christine K JohnsonEpiCenter for Disease Dynamics, School of Veterinary Medicine, University of California, Davis, 1089 Veterinary Medicine Drive, Davis, CA, 95616, USA. ckjohnson@ucdavis.edu.
Center for Disease Dynamics, Economics & Policy · USCenter for Molecular Dynamics - Nepal · NPUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efforts to mitigate the increasing emergence of antimicrobial resistance (AMR) will benefit from a One Health perspective, as over half of animal antimicrobials are also considered medically important in humans, and AMR can be maintained in the environment. This is especially pertinent to low- and middle-income countries and in community settings, where an estimated 80% of all antibiotics are used. This study features AMR genes found among humans, animals, and water at an urban informal settlement in Nepal with intensifying livestock production. We sampled humans, chickens, ducks, swine, and water clustered by household, as well as rodents and shrews near dwellings, concurrently in time in July 2017 in southeastern Kathmandu along the Manohara river. Real-time qualitative PCR was performed to screen for 88 genes. Our results characterize the animal-human-environmental interfaces related to the occurrence of specific resistance genes (bla

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsAnimalsChickensDrug Resistance, BacterialDrug Resistance, MicrobialHumansLivestockNepalPublic HealthSwineWaterAnti-Bacterial AgentsAnti-Infective AgentsWater

Identifiers

PMID35970981
PMCPMC9378709
OpenAlexW4291553051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.