Evidence map›Paper›PMID 35649651›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Imaging Dopaminergic Neurotransmission in Neurodegenerative Disorders.

Elon D Wallert, Elsmarieke van de Giessen, Remco J J Knol, Martijn Beudel, Rob M A de Bie, Jan Booij

Open access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  11. The radiotracer [Annals of nuclear medicine · 2026
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  18. CYP3A4 inhibitors may influence the quantification of [European journal of nuclear medicine and molecular imaging · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Elon D WallertDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Elsmarieke van de GiessenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
Remco J J KnolDepartment of Nuclear Medicine, Noordwest Ziekenhuisgroep, Alkmaar, The Netherlands; and.
Martijn BeudelDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Rob M A de BieDepartment of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Jan BooijDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands; j.booij@amsterdamumc.nl.
University of Amsterdam · NLAmsterdam University Medical Centers · NLNoordwest Ziekenhuisgroep · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Imaging of dopaminergic transmission in neurodegenerative disorders such as Parkinson disease (PD) or dementia with Lewy bodies plays a major role in clinical practice and in clinical research. We here review the role of imaging of the nigrostriatal pathway, as well as of striatal receptors and dopamine release, in common neurodegenerative disorders in clinical practice and research. Imaging of the nigrostriatal pathway has a high diagnostic accuracy to detect nigrostriatal degeneration in disorders characterized by nigrostriatal degeneration, such as PD and dementia with Lewy bodies, and disorders of more clinical importance, namely in patients with clinically uncertain parkinsonism. Imaging of striatal dopamine D

Indexed as

Lewy Body DiseaseNeurodegenerative DiseasesParkinson DiseaseParkinsonian DisordersDiagnostic ImagingDopamineHumansSynaptic TransmissionDopaminedopamineneurodegenerationParkinsonPETSPECT

Identifiers

PMID35649651
PMCPMC9165729
OpenAlexW4281976913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.