Evidence map›Paper›PMID 35558411›Full record

ArticleRSC advances2018

Selective and sensitive detection of cinnamaldehyde by nitrogen and sulphur co-doped carbon dots: a detailed systematic study.

Suraj Konar, Dipanjan Samanta, Subhajit Mandal, Subhayan Das, Madhusudan Kr Mahto, Manisha Shaw, Mahitosh Mandal, Amita Pathak

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Suraj KonarDepartment of Chemistry, Indian Institute of Technology Kharagpur West Bengal 721302 India ami@chem.iitkgp.ernet.in +91-3222-281922 +91-9434-038730.ORCID https://orcid.org/0000-0002-1576-3743
Dipanjan SamantaDepartment of Chemistry, Indian Institute of Technology Kharagpur West Bengal 721302 India ami@chem.iitkgp.ernet.in +91-3222-281922 +91-9434-038730.
Subhajit MandalSchool of Chemical Sciences, Indian Association for the Cultivation of Science Kolkata West Bengal 700032 India.ORCID https://orcid.org/0000-0001-9948-8517
Subhayan DasSchool of Medical Science and Technology, Indian Institute of Technology Kharagpur West Bengal 721302 India.ORCID https://orcid.org/0000-0002-8628-5128
Madhusudan Kr MahtoDepartment of Chemistry, Indian Institute of Technology Kharagpur West Bengal 721302 India ami@chem.iitkgp.ernet.in +91-3222-281922 +91-9434-038730.
Manisha ShawDepartment of Chemistry, Indian Institute of Technology Kharagpur West Bengal 721302 India ami@chem.iitkgp.ernet.in +91-3222-281922 +91-9434-038730.
Mahitosh MandalSchool of Medical Science and Technology, Indian Institute of Technology Kharagpur West Bengal 721302 India.
Amita PathakDepartment of Chemistry, Indian Institute of Technology Kharagpur West Bengal 721302 India ami@chem.iitkgp.ernet.in +91-3222-281922 +91-9434-038730.
Indian Institute of Technology Kharagpur · INIndian Association for the Cultivation of Science · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrogen and sulfur co-doped carbon dots (NSCDs) synthesized through one-pot microwave-assisted pyrolysis of tartaric acid and thioacetamide have been used as a fluorescent probe for the sensitive and selective detection of clinically important organic aldehyde cinnamaldehyde. The as-prepared NSCDs displayed blue fluorescence (∼12% quantum yield), excellent aqueous solubility along with pH and excitation wavelength dependent emission behavior. In comparison to other aldehydes (formaldehyde, acetaldehyde, propionaldehyde, butyraldehyde, valeraldehyde, hexanal, crotonaldehyde and benzaldehyde) the fluorescence intensity of NSCDs was significantly quenched in the presence of cinnamaldehyde and the reduced intensity was linearly proportional to the concentration of cinnamaldehyde in the range of 0-15 mM with a detection limit of 99.0 μM. The fluorescence quenching of NSCDs was mainly attributed to the photo-excited electron transfer between NSCDs and aldehydes which was confirmed by measuring the life-time through time-resolved luminescence spectroscopy, energy levels of NSCDs through cyclic voltammetry (CV) and energy levels of aldehydes by density functional theory (DFT) based analyses. MTT assay of the NSCDs also proved their good biocompatibility and low toxicity towards human fibroblast cells thereby validating their suitability as a biologically relevant fluorescent probe for sensing cinnamaldehyde.

Identifiers

PMID35558411
PMCPMC9092083
OpenAlexW2904852778

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.