ArticleBMC geriatrics2022
Association between stress hyperglycemia ratio and delirium in older hospitalized patients: a cohort study.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- The role of diabetes mellitus on delirium onset: a systematic review and meta-analysis.Cardiovascular diabetology · 2025 · on this mapPooled it
- Relationship between stress hyperglycaemic ratio (SHR) and critical illness: a systematic review.Cardiovascular diabetology · 2025Pooled it
- Association between stress hyperglycemia ratio and 72-hour delirium in critically ill patients: A retrospective cohort study from the MIMIC-IV database.Metabolism open · 2026Article
- Association between the preoperative stress hyperglycemia ratio and postoperative delirium in older adults undergoing non-cardiac surgery: a retrospective cohort study.European geriatric medicine · 2026Article
- Association of stress hyperglycemia ratio with malnutrition, sarcopenia, and frailty in older adults: a cross-sectional study.BMC geriatrics · 2026Article
- Association between stress hyperglycemia ratio and cognitive function in older patients with diabetes or prediabetes: a cross-sectional study from the NHANES.Endocrine journal · 2026Article
- The Association Between Stress-Induced Hyperglycemia Ratio and Increased Urinary Albumin Excretion in Patients With Hypertension: A Population-Based Study.The Kaohsiung journal of medical sciences · 2026Article
- Association between hemoglobin glycation index and delirium after gastric surgery: Based upon the MIMIC-IV.Medicine · 2026Article
- High glucose-to-lymphocyte ratio increases the risk of delirium and all-cause mortality in intensive care unit patients.Scientific reports · 2026Article
- Association of stress hyperglycemia ratio with the incidence of delirium in critically ill patients: a retrospective cohort study with exploratory machine-learning analyses.BMC neurology · 2026Article
- Association between stress hyperglycemia ratio and ICU delirium among critically ill adults in MIMIC-IV.Scientific reports · 2026Article
- Diabetes and postoperative cognitive dysfunction and delirium in adults: mechanisms, biomarkers, and clinical management.Frontiers in endocrinology · 2026Review
- Association between stress hyperglycemic ratio and stroke in older people with metabolic syndrome: a prospective cohort study from UK Biobank.Frontiers in endocrinology · 2026Article
- J-shaped relationship between stress hyperglycemia ratio and delirium risk in critically ill patients: A population-based study.PloS one · 2026Article
- Association between stress hyperglycemia ratio and delirium risk in elderly surgical patients: a retrospective cohort study.BMC geriatrics · 2025Article
- Association between stress hyperglycemia ratio and post-stroke delirium in critically ill patients with ischemic stroke: an MIMIC-IV database analysis.European journal of medical research · 2025Article
- Assessment of stress hyperglycemia ratio as a prognostic indicator in geriatric intensive care patients experiencing delirium: a retrospective cohort analysis.European journal of medical research · 2025Article
- The Association Between Frequency of Fingertip Blood Glucose Measurement and Delirium in Intensive Care Unit Patients: A Retrospective Study Based on the MIMIC-IV Database.Nursing in critical care · 2025Article
- Stress hyperglycemia ratio and 30-day mortality among critically ill patients with acute heart failure: analysis of the MIMIC-IV database.Acta diabetologica · 2025Article
- Association between the glucose-to-potassium ratio and delirium in critically ill ICU patients: a retrospective study.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt remains unclear whether stress hyperglycemia is associated with delirium. We performed this cohort study to determine the association between stress hyperglycemia and delirium.
methodsWe consecutively enrolled patients aged ≥70 years who were admitted to the Geriatric Department of West China Hospital between March 2016 and July 2017. Stress hyperglycemia ratio (SHR) was calculated as fasting blood glucose divided by estimated average glucose derived from glycosylated hemoglobin (HbA1c) and was classified into three tertiles. Delirium was screened within 24 h of admission and three times daily thereafter, using the confusion assessment method. The Cox proportional hazards models were used to assess the association of SHR with delirium.
resultsAmong 487 included patients (mean age 83.0 years, 72.0% male), 50 (10.3%) patients experienced delirium during hospitalization. Compared to the second tertile, both the lowest and the highest SHR tertiles were independently associated with delirium (hazard ratio [HR] 3.71, 95% confidence interval [CI] 1.45-9.51; and HR 2.97, 95% CI 1.29-6.81, respectively). Similar results were found after further adjusting for statin comedication. Multiple-adjusted restricted cubic splines revealed a nonlinear relationship between SHR and delirium (P
conclusionsBoth lower and higher SHR were associated with increased risk of delirium but only in patients with HbA1c <6.5%. Admission SHR may serve as a promising predictor of delirium, and incorporating this biomarker into prediction algorithms might have potential clinical utility in aiding delirium risk stratification, especially in those with HbA1c <6.5%.
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