← Insulin × glycemic control

SynthesisCardiovascular diabetology2025

The role of diabetes mellitus on delirium onset: a systematic review and meta-analysis.

Klara Komici et al.PubMed ↗Full text ↗Publisher ↗

  • Intranasal insulin administrationlooks good hereLower delirium onset.Randomised, small.

What the trial testedrandomised · 2025

Randomised vs placebo groups

Probably lowered delirium onset

−66%−77% to −48%

Intranasal insulin administration vs placebo groups

Bigger than 7 in 10 for glycemic control

As reported

RR 0.34, 95% CI 0.23–0.52

Who was studied, and how

people with type 2 diabetes, in this paper

The trial randomly assignedassigned by chance

Intranasal insulin administration
placebo groups

Probably lowered delirium onset−66%

randomised

the abstract, start to end

… groups was characterized by a RR = 0.34 (95% CI 0.23-0.52).

← favours treatmentfavours comparator →
could be chance
Delirium onsetIntranasal insulin administration vs placebo groups
RR 0.340.23–0.52
InsulinGlycemic control

Insulin × glycemic controlhelps?mixed

unlikelylikely
0.50not counted
← favours comparatorfavours treatment →
more certainless certain
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7 papers cite it

2025
2026
this papercites it
Full record →Abstract, authors, funding and every citing paper · PMID 40390076