Evidence map›Paper›PMID 35250147›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2019

Design and Control of a Compact, Modular Robot for Transbronchial Lung Biopsy.

Stephanie Amack, Margaret Rox, Jason Mitchell, Tayfun Efe Ertop, Maxwell Emerson, Alan Kuntz, Fabien Maldonado, Jason Akulian, Joshua Gafford, Ron Alterovitz and 1 more

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. A System for Endoscopic Submucosal Dissection Featuring Concentric Push-Pull Manipulators.IEEE International Conference on Robotics and Automation : ICRA : [proceedings]. IEEE International Conference on Robotics and Automation · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Backward Planning for a Multi-Stage Steerable Needle Lung Robot.IEEE robotics and automation letters · 2021
    Article
  6. A Recurrent Neural Network Approach to Roll Estimation for Needle Steering.Experimental robotics : the ... international symposium · 2021
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephanie AmackMechanical Engineering, Vanderbilt University, Nashville, TN, USA.
Margaret RoxMechanical Engineering, Vanderbilt University, Nashville, TN, USA.
Jason MitchellMechanical Engineering, Vanderbilt University, Nashville, TN, USA.
Tayfun Efe ErtopMechanical Engineering, Vanderbilt University, Nashville, TN, USA.
Maxwell EmersonMechanical Engineering, Vanderbilt University, Nashville, TN, USA.
Alan KuntzComputer Science, University of North Carolina at Chapel Hill, NC, USA.
Fabien MaldonadoInterventional Pulmonology, Vanderbilt University Medical Center, Nashville, TN, USA.
Jason AkulianInterventional Pulmonology, University of North Carolina at Chapel Hill, NC, USA.
Joshua GaffordMechanical Engineering, Vanderbilt University, Nashville, TN, USA.
Ron AlterovitzComputer Science, University of North Carolina at Chapel Hill, NC, USA.
Robert J WebsterMechanical Engineering, Vanderbilt University, Nashville, TN, USA.

Funding

Bronchoscopic Steerable Needles for Transparenchymal Access to Lung NodulesR01EB024864 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ALTEROVITZ, RON · 2017 to 2021
$2.5M
Training Program for Innovative Engineering Research in Surgery and InterventionT32EB021937 · NIBIB · VANDERBILT UNIVERSITY · PI Dario J Englot, Michael Ian Miga · 2016 to 2026
$2.3M
NIBIB NIH HHS R01 EB024864NIBIB NIH HHS T32 EB021937
6 · The paper itself

Abstract

Lung cancer is one of the most prevalent and deadly forms of cancer, claiming more than 154,000 lives in the USA per year. Accurate targeting and biopsy of pulmonary abnormalities is key for early diagnosis and successful treatment. Many cancerous lesions originate in the peripheral regions of the lung which are not directly accessible from the bronchial tree, thereby requiring percutaneous approaches to collect biopsies, which carry a higher risk of pneumothorax, hemorrhage, and death in extreme cases. In prior work, our group proposed a concept for accessing the peripheral lung through the airways, via a bronchscope deployed steerable needle. In this paper, we present a more compact, modular, multi-stage robot, designed to deploy a steerable needle through a standard flexible bronchoscope, to retrieve biopsies from lesions in the peripheral regions of the lung. The robot has several stages that can control a steerable biopsy needle, as well as concentric tubes, which act as an aiming conduit. The functionality of this robot is demonstrated via closed-loop lesion targeting in a CT scanner. The steerable needle is controlled using a previously proposed sliding mode controller, based on feedback from a magnetic tracker embedded in the steerable needle's tip. Towards developing a clinically viable platform, this system builds on prior work through its modular, compact form factor, and workflow-conscious design that provides precise homing and the ability to interchange tools as needed.

Indexed as

BiopsyBronchoscopyLung CancerMinimally-Invasive SurgeryRobotics

Identifiers

PMID35250147
PMCPMC8898049

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.