Evidence map›Paper›PMID 35219848›Full record

ReviewFree radical biology & medicine2022

Mammalian peroxidasin (PXDN): From physiology to pathology.

Guangjie Cheng, Ruizheng Shi

Open access · greenAbstract readReview
In one paragraph

Review in Free radical biology & medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. DNA Methylation Variation in Blood Cells may Impact Platelet Function.TH open : companion journal to thrombosis and haemostasis · 2026
    Article
  9. Article
  10. Article
  11. PXDN regulated by WTAP/YTHDF1-mediated mJournal of experimental & clinical cancer research : CR · 2025
    Article
  12. Article
  13. Hemocyanin controlsVirulence · 2025
    Article
  14. Article
  15. Article
  16. Transcriptome analysis of the aortic coarctation area.Journal of molecular and cellular cardiology plus · 2024
    Article
  17. Article
  18. DNA Methylation ofBiomolecules · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Guangjie ChengDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States. Electronic address: guangjiecheng@uabmc.edu.
Ruizheng ShiDepartment of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, China.
University of Alabama at Birmingham · USXiangya Hospital Central South University · CN

Funding

A novel peroxidase in vascular endothelium and the development of atherosclerosisR01HL086836 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHENG, GUANGJIE · 2008 to 2012
$1.7M
The Roles of LPS-Binding Protein Vascular Peroxidase-1 in Innate ImmunityR01AI141724 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHENG, GUANGJIE · 2019 to 2022
$1.5M
Dual Function of VPO1 in Pathogen Recognition and KillingR21AI101642 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHENG, GUANGJIE · 2012 to 2013
$392k
VPO1 Protects from Endotoxin-Mediated Inflammation and Septic ShockR21AI139900 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CHENG, GUANGJIE · 2019 to 2020
$358k
NHLBI NIH HHS R01 HL086836NIAID NIH HHS R01 AI141724NIAID NIH HHS R21 AI101642NIAID NIH HHS R21 AI139900
6 · The paper itself

Abstract

Heme-containing peroxidases catalyze the oxidation of a variety of substrates by consuming hydrogen peroxide (H

Indexed as

Hydrogen PeroxidePeroxidaseAnimalsDeoxyribonucleosidesExtracellular Matrix ProteinsHumansMammalsPeroxidasesPeroxidasinPurine Nucleosides5'-O-(9-phenylxanthen-9-yl)-2'-deoxynebularineDeoxyribonucleosidesExtracellular Matrix ProteinsHydrogen PeroxidePeroxidasePeroxidasesPeroxidasinPurine NucleosidesCardiovascular diseaseCell signalingEnzymeGene mutationHeme PeroxidaseInnate immunityPathologyPeroxidasinPhysiology

Identifiers

PMID35219848
PMCPMC8957557
OpenAlexW4213419388

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.