ReviewNanomaterials (Basel, Switzerland)2022
How the Physicochemical Properties of Manufactured Nanomaterials Affect Their Performance in Dispersion and Their Applications in Biomedicine: A Review.
Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Nanomedicine-Integrated Phototherapy for Cancer Theranostics: A Systematic Review of Photoresponsive Materials, Mechanisms, and Clinical Translation.International journal of nanomedicine · 2026Pooled it
- Genotoxic and Physiological Responses to Repeated Exposure to Low-Concentration Silver Nanoparticles inInternational journal of molecular sciences · 2026Article
- Electronic Waste-Derived Nanomaterials: Environmental Release, Toxicity, and Public Health Risks.Nanomaterials (Basel, Switzerland) · 2026Review
- Nanomaterial-nucleic acid probe synergy: accelerating rapid pathogen detection and antimicrobial susceptibility testing in bloodstream infections.Folia microbiologica · 2026Review
- Improving Postharvest Quality of 'Tango' Mandarin Using a Preharvest Sonicated Nanoemulsion-Based Delivery System of Methyl Jasmonate and 1-Naphthaleneacetic Acid.Foods (Basel, Switzerland) · 2026Article
- Phytofabricated zinc oxide nanoparticles (ZnO-NPs) from a medicinal salt-tolerant Oxystelma esculentum (L.f.) Sm. extract and their multifunctional biological activities.Scientific reports · 2026Article
- Phytofabrication of Zinc Oxide Nanoparticles UsingBioinorganic chemistry and applications · 2026Article
- Enhanced Killing of Colon Cancer Cells by Mesoporous Silica Nanoparticles Loaded with Ellagic Acid.Nanomaterials (Basel, Switzerland) · 2025Article
- Inhalable Nanomaterial Discoveries for Lung Cancer Therapy: A Review.Pharmaceutics · 2025Review
- Biomedical Application of Nanogels: From Cancer to Wound Healing.Molecules (Basel, Switzerland) · 2025Review
- Inflammation Factors and Genistein Supplementation in Cancer-Preliminary Research.Current issues in molecular biology · 2024Article
- Metal-organic frameworks: Drug delivery applications and future prospects.ADMET & DMPK · 2024Review
- The Application of Nanogels as Efficient Drug Delivery Platforms for Dermal/Transdermal Delivery.Gels (Basel, Switzerland) · 2023Review
- Nanotechnology Involved in Treating Urinary Tract Infections: An Overview.Nanomaterials (Basel, Switzerland) · 2023Review
- A Review of in vivo Toxicity of Quantum Dots in Animal Models.International journal of nanomedicine · 2023Review
- Gold nanoparticles capped with L-glycine, L-cystine, and L-tyrosine: toxicity profiling and antioxidant potential.Journal of materials science · 2023Article
- Silver Nanoparticles Conjugated with Colistin Enhanced the Antimicrobial Activity against Gram-Negative Bacteria.Molecules (Basel, Switzerland) · 2022Article
- Toxicologic Concerns with Current Medical Nanoparticles.International journal of molecular sciences · 2022Review
- Tuning the Physicochemical Properties of Nanostructured Materials through Advanced Preparation Methods.Nanomaterials (Basel, Switzerland) · 2022Article
- Targeting Tumor Microenvironment by Metal Peroxide Nanoparticles in Cancer Therapy.Bioinorganic chemistry and applications · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The growth in novel synthesis methods and in the range of possible applications has led to the development of a large variety of manufactured nanomaterials (MNMs), which can, in principle, come into close contact with humans and be dispersed in the environment. The nanomaterials interact with the surrounding environment, this being either the proteins and/or cells in a biological medium or the matrix constituent in a dispersion or composite, and an interface is formed whose properties depend on the physicochemical interactions and on colloidal forces. The development of predictive relationships between the characteristics of individual MNMs and their potential practical use critically depends on how the key parameters of MNMs, such as the size, shape, surface chemistry, surface charge, surface coating, etc., affect the behavior in a test medium. This relationship between the biophysicochemical properties of the MNMs and their practical use is defined as their functionality; understanding this relationship is very important for the safe use of these nanomaterials. In this mini review, we attempt to identify the key parameters of nanomaterials and establish a relationship between these and the main MNM functionalities, which would play an important role in the safe design of MNMs; thus, reducing the possible health and environmental risks early on in the innovation process, when the functionality of a nanomaterial and its toxicity/safety will be taken into account in an integrated way. This review aims to contribute to a decision tree strategy for the optimum design of safe nanomaterials, by going beyond the compromise between functionality and safety.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.