Evidence map›Paper›PMID 34948436›Full record

ArticleInternational journal of molecular sciences2021

Highly Active Thermophilic L-Asparaginase from

Maria Dumina, Alexander Zhgun, Marina Pokrovskaya, Svetlana Aleksandrova, Dmitry Zhdanov, Nikolay Sokolov, Michael El'darov

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Thermostable bacterial L-asparaginase for polyacrylamide inhibition and in silico mutational analysis.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Maria DuminaGroup of Fungal Genetic Engineering, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, 117312 Moscow, Russia.
Alexander ZhgunGroup of Fungal Genetic Engineering, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, 117312 Moscow, Russia.ORCID 0000-0002-8672-8638
Marina PokrovskayaLaboratory of Medical Biotechnology, Institute of Biomedical Chemistry, 119121 Moscow, Russia.
Svetlana AleksandrovaLaboratory of Medical Biotechnology, Institute of Biomedical Chemistry, 119121 Moscow, Russia.
Dmitry ZhdanovLaboratory of Medical Biotechnology, Institute of Biomedical Chemistry, 119121 Moscow, Russia.ORCID 0000-0003-4753-7588
Nikolay SokolovLaboratory of Medical Biotechnology, Institute of Biomedical Chemistry, 119121 Moscow, Russia.
Michael El'darovGroup of Fungal Genetic Engineering, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, 117312 Moscow, Russia.
Institute of Biomedical Chemistry · RURussian Academy of Sciences · RU

Funding

Russian Foundation for Basic Research 19-08-01112
6 · The paper itself

Abstract

L-asparaginase (L-ASNase) is a biotechnologically relevant enzyme for the pharmaceutical, biosensor and food industries. Efforts to discover new promising L-ASNases for different fields of biotechnology have turned this group of enzymes into a growing family with amazing diversity. Here, we report that thermophile

Indexed as

Amino Acid SequenceAsparaginaseAsparagineBacteriaBacterial ProteinsEnzyme StabilityEvolution, MolecularGlutaminaseHot TemperatureHydrogen-Ion ConcentrationKineticsSequence AlignmentAsparaginaseAsparagineBacterial ProteinsGlutaminasebiochemical propertiescytotoxic activityheterologous expressionkinetic characteristicsL-asparaginasethermophile

Identifiers

PMID34948436
PMCPMC8709496
OpenAlexW4200519020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.