Evidence map›Paper›PMID 34945667›Full record

ReviewFoods (Basel, Switzerland)2021

Extracellular Matrix and the Production of Cultured Meat.

Khurshid Ahmad, Jeong-Ho Lim, Eun-Ju Lee, Hee-Jin Chun, Shahid Ali, Syed Sayeed Ahmad, Sibhghatulla Shaikh, Inho Choi

Open access · goldAbstract readReview
In one paragraph

Review in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Starch-Based Scaffolds for Cultivated Meat Production: Challenges and Perspectives.Comprehensive reviews in food science and food safety · 2025
    Review
  7. Review
  8. Article
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  11. Article
  12. Review
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Khurshid AhmadDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0002-1095-8445
Jeong-Ho LimDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0002-0375-8170
Eun-Ju LeeDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0003-2496-0463
Hee-Jin ChunDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.
Shahid AliDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0002-4724-5086
Syed Sayeed AhmadDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0002-2829-2768
Sibhghatulla ShaikhDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0002-7489-2393
Inho ChoiDepartment of Medical Biotechnology, Yeungnam University, Gyeongsan 38541, Korea.
Yeungnam University · KR

Funding

This work was supported by the 2019 Yeungnam University Research Grant. N/A
6 · The paper itself

Abstract

Cultured meat production is an evolving method of producing animal meat using tissue engineering techniques. Cells, chemical factors, and suitable biomaterials that serve as scaffolds are all essential for the cultivation of muscle tissue. Scaffolding is essential for the development of organized meat products resembling steaks because it provides the mechanical stability needed by cells to attach, differentiate, and mature. In in vivo settings, extracellular matrix (ECM) ensures substrates and scaffolds are provided for cells. The ECM of skeletal muscle (SM) maintains tissue elasticity, creates adhesion points for cells, provides a three-dimensional (3D) environment, and regulates biological processes. Consequently, creating mimics of native ECM is a difficult task. Animal-derived polymers like collagen are often regarded as the gold standard for producing scaffolds with ECM-like properties. Animal-free scaffolds are being investigated as a potential source of stable, chemically defined, low-cost materials for cultured meat production. In this review, we explore the influence of ECM on myogenesis and its role as a scaffold and vital component to improve the efficacy of the culture media used to produce cultured meat.

Indexed as

cultured meatextracellular matrixscaffoldskeletal muscle

Identifiers

PMID34945667
PMCPMC8700801
OpenAlexW4200256904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.