Evidence map›Paper›PMID 34907720›Full record

ArticleJournal of applied biomedicine2019

Chokeberry juice supplementation in type 2 diabetic patients - impact on health status.

Milica Milutinovic, Radmila Velickovic Radovanovic, Katarina Savikin, Sasa Radenkovic, Marjan Arvandi, Milica Pesic, Milica Kostic, Bojana Miladinovic, Suzana Brankovic, Dusanka Kitic

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of applied biomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Impact of a Chokeberry (Nutrients · 2025
    Pooled it
  3. Effects ofThe review of diabetic studies : RDS · 2022
    Pooled it
  4. Trial
  5. Trial
  6. Polyphenols, Polysaccharides, and Their Complexes fromMolecules (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Article
  9. Functional Activities and Mechanisms ofCurrent issues in molecular biology · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. The Protective Potential ofInternational journal of molecular sciences · 2023
    Article
  15. Potential Benefits of Black Chokeberry (Molecules (Basel, Switzerland) · 2022
    Review
  16. Chokeberry (Nutrients · 2022
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Milica MilutinovicUniversity of Nis, Faculty of Medicine, Department of Pharmacy, Nis, Serbia.
Radmila Velickovic RadovanovicUniversity of Nis, Faculty of Medicine, Department of Pharmacology, Nis, Serbia.
Katarina SavikinInstitute for Medicinal Plants Research "Dr. Josif Pancic", Belgrade, Serbia.
Sasa RadenkovicUniversity of Nis, Faculty of Medicine, Department of Internal Medicine, Nis, Serbia.
Marjan ArvandiInstitute of Public Health, Medical Decision Making, and Health Technology Assessment, UMIT, Hall in Tirol, Austria.
Milica PesicUniversity of Nis, Faculty of Medicine, Department of Internal Medicine, Nis, Serbia.
Milica KosticUniversity of Nis, Faculty of Medicine, Department of Pharmacy, Nis, Serbia.
Bojana MiladinovicUniversity of Nis, Faculty of Medicine, Department of Pharmacy, Nis, Serbia.
Suzana BrankovicUniversity of Nis, Faculty of Medicine, Department of Physiology, Nis, Serbia.
Dusanka Kitic

Funding

Serbian Ministry of Education, Science and Technological Development III 41018Serbian Ministry of Education, Science and Technological Development III 46013
6 · The paper itself

Abstract

Recent literature evidence indicates the potential use of chokeberry preparations in the prevention and treatment of some chronic noncommunicable diseases. The aim of the present study was to evaluate the effects of the three months oral chokeberry juice supplementation in type 2 diabetic patients, as well as its influence on hematological parameters and certain parameters of the renal dysfunction. The study was designed as an open-label trial, which included 35 patients who have received the herbal supplement, polyphenol-rich chokeberry juice (150 ml/day, three times a day for 50 ml), in addition to their standard therapy. Chokeberry juice as a rich source of polyphenol compounds could be an effective preventive and therapeutic agent in diabetes mellitus type 2. Hematological and biochemical parameters were measured at baseline, after 3 months with the chokeberry juice supplementation and after the next 3 months without the chokeberry juice supplementation (follow-up period). Significant difference was noticed in the levels of LDL-cholesterol, glycated hemoglobin and serum creatinine (p < 0.05), as well as in the levels of some hematological parameters, such as white blood cell and lymphocyte count (p < 0.01), hematocrit, blood hemoglobin, mean corpuscular volume, hemoglobin and hemoglobin concentration and red blood cell count (p < 0.05). The daily consumption of the chokeberry juice could improve the health status in patients with type 2 diabetes mellitus, in combination with their standard therapy.

Indexed as

Aronia melanocarpaDiabetes mellitus type 2Hematological parametersJuiceRenal dysfunction

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.