ArticleAntioxidants (Basel, Switzerland)2021
Phenolic Analysis and In Vitro Biological Activity of Red Wine, Pomace and Grape Seeds Oil Derived from
Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.
- Grape pomace as a natural source of antimicrobial agents for food preservation.Frontiers in nutrition · 2025Pooled it
- A two-phase clustering procedure based on allele specific expression.BMC bioinformatics · 2026Article
- Multi-Omics Elucidation of Flavor Characteristics in Compound Fermented Beverages Based on Flavoromics and Metabolomics.Foods (Basel, Switzerland) · 2025Article
- Transylvanian Grape Pomaces as Sustainable Sources of Antioxidant Phenolics and Fatty Acids-A Study of White and Red Cultivars.Antioxidants (Basel, Switzerland) · 2025Article
- Evaluation of Bioactive Properties of Ultrasound-Assisted Extracts from Prokupac Grape Skins for Functional Foods.Antioxidants (Basel, Switzerland) · 2025Article
- Grape by-products from the wine industry - an untapped sustainable resource for application in animal skin health preservation and treatment.Frontiers in pharmacology · 2025Review
- Advances in Grape Seed Oil Extraction Techniques and Their Applications in Food Products: A Comprehensive Review and Bibliometric Analysis.Foods (Basel, Switzerland) · 2024Review
- Valorization of Grape Pomace: A Review of Phenolic Composition, Bioactivity, and Therapeutic Potential.Antioxidants (Basel, Switzerland) · 2024Review
- Chemical Composition and In Vitro Bioactivities of Extracts from Cones ofPlants (Basel, Switzerland) · 2024Article
- Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and Torrontés Wine Pomaces from the Calchaquíes Valleys (Argentina) for Their Sustainable Exploitation.Foods (Basel, Switzerland) · 2024Article
- Phytochemical Screening and Antidiabetic Efficacy ofACS omega · 2024Article
- Grape Pomace-Advances in Its Bioactivity, Health Benefits, and Food Applications.Foods (Basel, Switzerland) · 2024Review
- Nutraceutical Potential of Grape (Molecules (Basel, Switzerland) · 2023Review
- Antioxidant, Antiglaucoma, Anticholinergic, and Antidiabetic Effects of Kiwifruit (Life (Basel, Switzerland) · 2023Article
- Antibacterial Activity against Clinical Strains of a Natural Polyphenolic Extract from Albariño White Grape Marc.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Anti-SARS-CoV-2 Activity ofMolecules (Basel, Switzerland) · 2023Article
- Review
- Phenolic features and anthocyanin profiles in winemaking pomace and fresh berries of grapes with different pedigrees.Food science and biotechnology · 2023Article
- Evaluation of the Phytochemistry-Therapeutic Activity Relationship for Grape Seeds Oil.Life (Basel, Switzerland) · 2023Review
- Metabolomic Profiling and Assessment of Phenolic Compounds Derived from Vitis davidii Foex Cane and Stem ExtractsInternational journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Grape pomace is commonly considered a waste product of monovarietal red wine production. Methods: HPLC-DAD analysis was performed to determine the polyphenol and flavonoid contents of all the extracts obtained from Montepulciano d'Abruzzo red wine and grape skins whereas, GC-MS was applied to the determination of fatty acid composition in grape seeds oil. Biological characterization involves antioxidant and antimicrobial assays for all the extracts and seeds oil; Their ability to inhibit α-glucosidase, α-amylase, α-tyrosinase, and ChE enzymes was also detected, together with anti-inflammatory activity on wine, grape skin extracts, and seeds oil by lipoxygenase (5-LOX) and LPS-stimulated macrophage release assays. Data indicate significative polyphenols content (199.31 ± 7.21 mgGAE/g), antioxidant (CUPRAC assay (1036.98 mgTE/g)), enzymatic inhibition (α-tyrosinase: 151.30 ± 1.20 mgKAE/g) and anti-inflammatory activities for wine-organic extract 2, while the antimicrobial activity of grape skin decoction is higher than those reported by wine extracts on three bacterial strains. Interestingly only dealcoholized wine and wine-aqueous extract exerts inhibitory effects on α-glucosidase (20.62 ± 0.23 mmolACAE/g and 19.81 ± 0.03 mmolACAE/g, respectively), while seeds oil is rich in oleic and linoleic acids. These results confirm the strong antioxidant properties of Montepulciano d'Abruzzo grape pomace, suggesting the potential use of this waste product as functional food supplements in the human diet and in cosmeceutics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.