Evidence map›Paper›PMID 34827909›Full record

ArticleAnimals : an open access journal from MDPI2021

Genetic Diversity of Hepatitis E Virus Type 3 in Switzerland-From Stable to Table.

Isabelle Vonlanthen-Specker, Roger Stephan, Xaver Sidler, Dominik Moor, Cornel Fraefel, Claudia Bachofen

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Isabelle Vonlanthen-SpeckerInstitute of Virology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Roger StephanInstitute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0003-1002-4762
Xaver SidlerDepartment of Farm Animals, Division of Swine Medicine, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.
Dominik MoorRisk Assessment Division, Federal Food Safety and Veterinary Office FSVO, 3003 Bern, Switzerland.ORCID 0000-0003-1840-556X
Cornel FraefelInstitute of Virology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0001-7221-6706
Claudia BachofenInstitute of Virology, Vetsuisse Faculty, University of Zurich, 8057 Zurich, Switzerland.ORCID 0000-0002-0799-8083

Funding

Federal Food Safety and Veterinary Office 1.18.05
6 · The paper itself

Abstract

Hepatitis E caused by hepatitis E viruses of the genotype 3 (HEV-3) is a major health concern in industrialized countries and due to its zoonotic character requires a "One Health" approach to unravel routes and sources of transmission. Knowing the viral diversity present in reservoir hosts, i.e., pigs but also wild boars, is an important prerequisite for molecular epidemiology. The aim of this study was to gain primary information on the diversity of HEV-3 subtypes present along the food chain in Switzerland, as well as the diversity within these subtypes. To this end, samples of domestic pigs from slaughterhouses and carcass collection points, as well as from hunted wild boars, were tested for HEV RNA and antibodies. HEV positive meat products were provided by food testing labs. The HEV subtypes were determined using Sanger and next generation sequencing. The genetic analyses confirmed the predominance of a Swiss-specific cluster within subtype HEV-3h in pigs, meat products, and wild boars. This cluster, which may result from local virus evolution due to the isolated Swiss pig industry, supports fast differentiation of domestic and imported infections with HEV.

Indexed as

food chainhepatitis E virusone healthpigsubtypingSwitzerlandwild boar

Identifiers

PMID34827909
PMCPMC8614342

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.