Evidence map›Paper›PMID 34786371›Full record

ArticleAsia Pacific allergy2021

Identification of predictors for persistence of immediate-type egg allergy in Chinese children.

Noelle Anne Ngai, Agnes Sze Yin Leung, Jonathan Chi Ho Leung, Oi Man Chan, Ting Fan Leung

Open access · diamondAbstract read
In one paragraph

Article in Asia Pacific allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Factors predicting tolerance of egg allergy.The journal of allergy and clinical immunology. Global · 2026
    Article
  2. Review
  3. Vegan Egg: A Future-Proof Food Ingredient?Foods (Basel, Switzerland) · 2022
    Review
  4. Asia Pacific allergy · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Noelle Anne NgaiDepartment of Paediatrics, Prince of Wales Hospital, Shatin, Hong Kong.
Agnes Sze Yin LeungDepartment of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID https://orcid.org/0000-0001-8249-4478
Jonathan Chi Ho LeungFaculty of Science, The Chinese University of Hong Kong, Shatin, Hong Kong.
Oi Man ChanDepartment of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID https://orcid.org/0000-0001-8845-1428
Ting Fan LeungDepartment of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong.ORCID https://orcid.org/0000-0002-6469-1926
Prince of Wales Hospital · CNChinese University of Hong Kong · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEgg allergy is one of the most common food allergies in childhood with increasing prevalence in Hong Kong. While ample studies were published on its optimal diagnosis, there was limited data on predictors for the natural history of egg allergy in Asian populations.

objectiveThis study aimed to characterize the clinical course and outcome of children with egg allergy and identify its prognostic factors.

methodsAll Chinese children with immediate-type egg allergy being followed since ≥3 years old in allergy clinic of our university-affiliated teaching hospital were reviewed to determine if they outgrew egg allergy at the latest follow-up. The predictive values of clinical and atopic factors for resolution of egg allergy were analyzed on Kaplan-Meier curves, and factors independently associated with persistent egg allergy was analyzed by logistic regression.

resultsSeventy-six patients with median (interquartile range) age 8.9 years (6.3-13.0 years) were recruited. They initially presented with egg-allergic reactions at 1.0 years (0.7-1.7 years). Fifty-four children (71%) were able to tolerate egg at a median of 36 months from initial reaction. Patients with concomitant peanut allergy and those with initial reaction at ≥1 year old were more likely to have persistent egg allergy (

conclusionMost Chinese children with immediate-type egg allergy can tolerate egg in long run. SPT wheal size to egg, concomitant peanut allergy and initial presentation after infancy may predict egg allergy persistence.

Indexed as

Egg allergyNatural historyPeanut allergyPersistencePrediction

Identifiers

PMID34786371
PMCPMC8563105
OpenAlexW3211129685

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.