Evidence map›Paper›PMID 34718796›Full record

Observational studyPhysical therapy2022

Prevalence of Walking Limitation After Acute Stroke and Its Impact on Discharge to Home.

Dennis R Louie, Lisa A Simpson, W Ben Mortenson, Thalia S Field, Jennifer Yao, Janice J Eng

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Physical therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Article
  4. Review
  5. Distinct Patterns of Mobility Recovery After Stroke Using Routine Clinical Data.medRxiv : the preprint server for health sciences · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Home-Based Gait Interventions for Adults with Stroke: A Scoping Review.Archives of rehabilitation research and clinical translation · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dennis R LouieGraduate Program in Rehabilitation Sciences, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Lisa A SimpsonGraduate Program in Rehabilitation Sciences, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
W Ben MortensonRehabilitation Research Program, Vancouver Coastal Health Research Institute, Vancouver, Canada.
Thalia S FieldDivision of Neurology, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Jennifer YaoDivision of Physical Medicine and Rehabilitation, Department of Medicine, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
Janice J EngRehabilitation Research Program, Vancouver Coastal Health Research Institute, Vancouver, Canada.
Vancouver Coastal Health · CAVancouver Coastal Health Research Institute · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study was to provide contemporary estimates of the prevalence of lower extremity motor impairment and walking limitation after first-ever stroke and to characterize the predictive nature of early walking ability for being discharged home after acute hospitalization.

methodsIn this cohort study, data were collected from a metropolitan acute care hospital in Canada at admission for 487 adults with first-ever acute ischemic or hemorrhagic stroke. Lower extremity motor impairment and walking limitation were measured using the National Institutes of Health Stroke Scale and AlphaFIM, respectively. Parallel multivariable logistic regression models were built to predict discharge home after acute hospitalization compared with further hospitalization.

resultsFor patients surviving a first-ever stroke, 44.1% presented with some degree of lower extremity motor impairment and 46.0% were unable to walk. In a multivariable model built around a binary classification of walking (Nagelkerke R2 = 0.41), those with any ability to walk at admission (with or without therapist assistance) had 9.48 times greater odds of being discharged home (odds ratio = 9.48, 95% CI = 6.11-14.92) than those who were unable. In a parallel multivariable model built around an ordinal classification of walking (Nagelkerke R2 = 0.49), patients had 2.07 times greater odds (odds ratio = 2.07, 95% CI = 1.82-2.38) of being discharged home for each increment on a 6-point walking scale (total dependence to complete independence) assessed at acute admission.

conclusionApproximately one-half of patients with first-ever stroke present with lower extremity weakness and walking limitation. Early walking ability is a significant predictor of returning home after acute hospitalization, independent of stroke severity. Discharge planning may be facilitated early after stroke with the familiar assessment of walking ability. IMPACT: An early assessment of walking function within days of stroke admission can help to streamline discharge planning. LAY SUMMARY: Nearly one-half of all individuals who experience a first-time stroke have walking difficulty when they arrive at the hospital. The severity of the walking limitation can predict whether a patient will eventually be discharged home or go on to further hospitalization.

Indexed as

Mobility LimitationPatient DischargeAgedAged, 80 and overCohort StudiesFemaleGait Disorders, NeurologicHospitalizationHumansMaleMiddle AgedPredictive Value of TestsPrevalenceStroke RehabilitationWalkingLower ExtremityPrognosisStrokeWalking

Identifiers

PMID34718796
PMCPMC8787995
OpenAlexW3210493891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.