Evidence map›Paper›PMID 34682732›Full record

ArticleInternational journal of environmental research and public health2021

Partial Replacement of Dietary Fat with Polyunsaturated Fatty Acids Attenuates the Lipopolysaccharide-Induced Hepatic Inflammation in Sprague-Dawley Rats Fed a High-Fat Diet.

Hee-Kyoung Son, Huo Xiang, Seohyun Park, Jisu Lee, Jae-Joon Lee, Sunyoon Jung, Jung-Heun Ha

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Nutrients · 2025
    Article
  2. Article
  3. Article
  4. Partial replacement of high-fat diet withFrontiers in nutrition · 2023
    Article
  5. LoweringInternational journal of molecular sciences · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hee-Kyoung SonResearch Center for Industrialization of Natural Neutralization, Dankook University, Cheonan 31116, Korea.
Huo XiangResearch Center for Industrialization of Natural Neutralization, Dankook University, Cheonan 31116, Korea.
Seohyun ParkResearch Center for Industrialization of Natural Neutralization, Dankook University, Cheonan 31116, Korea.
Jisu LeeResearch Center for Industrialization of Natural Neutralization, Dankook University, Cheonan 31116, Korea.
Jae-Joon LeeDepartment of Food and Nutrition, Chosun University, Gwangju 61452, Korea.ORCID 0000-0001-5737-612X
Sunyoon JungResearch Center for Industrialization of Natural Neutralization, Dankook University, Cheonan 31116, Korea.ORCID 0000-0001-9217-5649
Jung-Heun HaResearch Center for Industrialization of Natural Neutralization, Dankook University, Cheonan 31116, Korea.ORCID 0000-0001-5282-531X
Dankook University · KRChosun University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated whether the partial replacement of dietary fat with polyunsaturated fatty acids (PUFAs) ameliorated the lipopolysaccharide (LPS)-induced hepatic inflammation in rats fed a high-fat diet. Male Sprague-Dawley rats were divided into three groups and provided each of the following diets: (1) high-fat diet (HFD), (2) HFD with perilla oil (PO), and (3) HFD with corn oil (CO). After 12 weeks of dietary intervention, the rats were intraperitoneally injected with LPS (5 mg/kg) from

Indexed as

Dietary FatsDiet, High-FatAnimalsFatty AcidsFatty Acids, UnsaturatedInflammationLipopolysaccharidesLiverMaleRatsRats, Sprague-DawleyDietary FatsFatty AcidsFatty Acids, UnsaturatedLipopolysaccharidescorn oilhigh-fat dietinflammationlipopolysaccharideperilla oilpolyunsaturated fatty acids

Identifiers

PMID34682732
PMCPMC8535618
OpenAlexW3207298272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.